Results 71 to 80 of about 401,550 (291)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Exogenous Phytohormones Modulate Mycorrhiza-Induced Changes in Root Hair Configuration of Trifoliate Orange

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2016
Mycorrhizas alter root hair profile, but it is not clear whether exogenous phytohormones regulate the mycorrhizal effects on root hair. Studies were carried out in a two-chambered rootbox separated by 37-μm nylon mesh to establish root+hyphae chamber ...
Chun-Yan LIU, A.K. SRIVASTAVA, De-Jian ZHANG, Ying-Ning ZOU, Qiang-Sheng Wu   +4 more
doaj   +1 more source

Loss-of-function of MEDIATOR 12 or 13 subunits causes the swelling of root hairs in response to sucrose and abscisic acid in Arabidopsis

Plant Signaling & Behavior, 2023
Root hairs are epidermal cell extensions that increase the root surface for water and nutrient acquisition. Thus, both the initiation and elongation of root hairs are critical for soil exploration and plant adaptation to ever changing growth conditions ...
Javier Raya-González, José Carlos Prado-Rodríguez, León Francisco Ruiz-Herrera, José López-Bucio   +3 more
doaj   +1 more source

Root Hair-Specific EXPANSIN B Genes Have Been Selected for Graminaceae Root Hairs

Molecules and Cells, 2010
Cell differentiation ultimately relies on the regulation of cell type-specific genes. For a root hair cell to undergo morphogenesis, diverse cellular processes including cell-wall loosening must occur in a root hair cell-specific manner. Previously, we identified and characterized root hairspecific cis-elements (RHE) from the genes encoding the cell ...
Su-Kyung, Won, Sang-Bong, Choi, Simple, Kumari, Misuk, Cho, Sang Ho, Lee, Hyung-Taeg, Cho   +5 more
openaire   +2 more sources

Hormonal Solution for (Root) Hair Extension [PDF]

The Plant Cell, 2020
Root hairs are tubular outgrowths of a subset of root epidermal cells serving multiple roles, including plant anchorage in the soil, water and nutrient absorption, and symbiotic interactions with nitrogen-fixing bacteria in legumes ([Salazar-Henao et al., 2016][1]).
openaire   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

An ectomycorrhizal fungus alters sensitivity to jasmonate, salicylate, gibberellin, and ethylene in host roots. [PDF]

, 2020
The phytohormones jasmonate, gibberellin, salicylate, and ethylene regulate an interconnected reprogramming network integrating root development with plant responses against microbes.
Amirebrahimi, Mojgan, Barry, Kerrie W, Basso, Veronica, Block, Jonathan, Daguerre, Yohann, Grigoriev, Igor V, Guinet, Frédéric, Kohler, Annegret, Martin, Francis, Miyauchi, Shingo, Na, Hyunsoo, Novák, Ondřej, Singan, Vasanth, Veneault-Fourrey, Claire, Šimura, Jan   +14 more
core   +3 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

OsNOX3, encoding a NADPH oxidase, regulates root hair initiation and elongation in rice

Biologia Plantarum, 2018
Root hairs play important roles in plant nutrient and water acquisition. To better understand the genetic mechanism controlling root hair development in rice (Oryza sativa L.), a rice mutant with root hair defects was isolated and characterized.
S. S. Wang, X. N. Zhu, J. X. Lin, W. J. Zheng, B. T. Zhang, J. Q. Zhou, J. Ni, Z. C. Pan, S. H. Zhu, W. N. Ding   +9 more
doaj   +1 more source

High resolution synchrotron imaging of wheat root hairs growing in soil and image based modelling of phosphate uptake

, 2013
Root hairs are known to be highly important for uptake of sparingly soluble nutrients, particularly in nutrient deficient soils. Development of increasingly sophisticated mathematical models has allowed uptake characteristics to be quantified.
Alan Marchant, Barber, Bates, Bates, Bernd R. Pinzer, Datta, Davey L. Jones, Defra, Ehrhardt, Esser, Gahoonia, Gahoonia, Gahoonia, Gahoonia, Giesler, Hinsinger, Ian Sinclair, Keith R. Daly, Leitner, Ma, Murphy, Neil J. Gostling, Peter Talboys, Richard Boardman, Samuel D. Keyes, Schnepf, Schnepf, Schnepf, Schnepf, Schnepf, Smith, Thonar, Tiina Roose, Tinker, Vaccari, Watt, Zygalakis   +36 more
core   +1 more source