Results 21 to 30 of about 266,135 (214)

Research on Soil Moisture Inversion Method for Canal Slope of the Middle Route Project of the South to North Water Transfer Based on GNSS-R and Deep Learning

open access: yesRemote Sensing, 2023
The soil moisture from the South-to-North Water Diversion Middle Route Project is assessed in this study. Complex and variable geological conditions complicate the prediction of soil moisture in the study area.
Qingfeng Hu   +10 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

An Analytical Derivation of the Signal-in-Space Root-Mean-Square User Range Error

open access: yesNavigation
The concept of the signal-in-space (SIS) root-mean-square (RMS) user range error (URE) is used to evaluate the performance of multiple global navigation satellite systems (GNSSs); however, a complete analytical derivation has not been published.
Brent Renfro   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Models of criterion evaluation of the image processing systems effectiveness

open access: yesЗбірник наукових праць Державного університету інфраструктури та технологій: серія "Транспортні системи і технології", 2023
The criteria used to evaluate the effectiveness of image processing systems are investigated in the article. The requirements for performance criteria are analyzed.
O. Gertsiy
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Forecast Assessment of CMA-GFS on the Meteorological Elements in the Northeast Hemisphere

open access: yesGaoyuan qixiang, 2023
Based on the daily forecast data initialized at 20:00 (Beijing time) of the CMA global forecast system (CMA-GFS) during the period from October, 2019 to December, 2020, the forecasting quality of the upper air meteorological elements in the Northeast ...
Chunjuan QI, Liujie PAN
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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