Results 41 to 50 of about 270,750 (256)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

“Smart agriculture: a climate-driven approach to modelling and forecasting fall armyworm populations in maize using machine learning algorithms”

Frontiers in Plant Science
The fall armyworm (Spodoptera frugiperda) poses a significant threat to global maize production owing to its rapid life cycle, extensive host range, and strong dispersal capabilities. We developed a forecasting system for fall armyworm outbreaks over one
Vani Sree Kalisetti, Upendhar Sudharshanam, Nagesh Kumar Mallela Venkata, Rajashekhar Mandla, Srinivas Akula, Mallaiah Bedika, Bhadru Dharavath, Sreelatha Dogga, Ramakrishna Babu A, Chandrasekhar Javaji   +9 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

A general formula for calculating surface area of the similarly shaped leaves: Evidence from six Magnoliaceae species

Global Ecology and Conservation, 2020
Leaf area is an important indicator of photosynthetic capacity in plants. Knowledge of the variation of leaf shape at an individual level or a population level can help by accurately calculate leaf area.
Jiayan He, Gadi V.P. Reddy, Mengdi Liu, Peijian Shi   +3 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Analysis of the Mean Absolute Error (MAE) and the Root Mean Square Error (RMSE) in Assessing Rounding Model

IOP Conference Series: Materials Science and Engineering, 2018
Most existing Collaborative Filtering (CF) algorithms predict a rating as the preference of an active user toward a given item, which is always a decimal fraction. Meanwhile, the actual ratings in most data sets are integers. In this paper, we discuss and demonstrate why rounding can bring different influences to these two metrics; prove that rounding ...
Weijie Wang, Yanmin Lu
openaire   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Predictive model for congenital heart disease in children of Pakistan by using structural equation modeling

BMC Medical Informatics and Decision Making
Background The structural abnormality of the heart and its blood vessels at the time of birth is known as congenital heart disease. Every year in Pakistan, sixty thousand children are born with CHD, and 44 in 1000 die before they are a month old. Various
Sana Shahid, Haris Khurram, Muhammad Ahmed Shehzad, Muhammad Aslam   +3 more
doaj   +1 more source

Research on Parameter Inversion of Coal Mining Subsidence Prediction Model Based on Improved Whale Optimization Algorithm

Energies
Rapid coal mining results in a series of mining subsidence damages. Predicting surface movement and deformation accurately is essential to reducing mining damage.
Qingbiao Guo, Boqing Qiao, Yingming Yang, Junting Guo   +3 more
doaj   +1 more source

Potential root mean square error skill score

Journal of Renewable and Sustainable Energy
Consistency, in a narrow sense, denotes the alignment between the forecast-optimization strategy and the verification directive. The current recommended deterministic solar forecast verification practice is to report the skill score based on root mean square error (RMSE), which would violate the notion of consistency if the forecasts are optimized ...
Martin János Mayer, Dazhi Yang
openaire   +3 more sources