Results 41 to 50 of about 266,135 (214)
EnergiesRapid coal mining results in a series of mining subsidence damages. Predicting surface movement and deformation accurately is essential to reducing mining damage.
Qingbiao Guo +3 more
doaj +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Results in EngineeringThis study explores using the Multiverse Optimization Algorithm to estimate the material properties of thermoelectric generators used for power generation. The modeling of these modules is complex due to nonlinear differential equations and the challenge
Luis Fernando Grisales-Noreña +4 more
doaj +1 more source
Waveform Agile Sensing Approach for Tracking Benchmark in the Presence of ECM using IMMPDAF [PDF]
Radioengineering, 2017 This paper presents an efficient approach based on waveform agile sensing, to enhance the performance of benchmark target tracking in the presence of strong interference.
G. S. Satapathi, S. Pathipati
doaj
Energy Exploration & Exploitation, 2018 This study presents a prediction technique for the output current of a photovoltaic grid-connected system by using random forests technique. Experimental data of a photovoltaic grid-connected system are used to train and validate the proposed model ...
Ibrahim A Ibrahim +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Rapid determination of tannin in Danshen and Guanxinning injections using UV spectrophotometry for quality control [PDF]
Journal of Innovative Optical Health Sciences, 2018 A technique for the determination of tannin content in traditional Chinese medicine injections (TCMI) was developed based on ultraviolet (UV) spectroscopy.
Hongxia Huang +5 more
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source