Results 121 to 130 of about 196,182 (303)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Unpredictable Root Canal Morphology: Expect the Unexpected

Advances in Human Biology, 2015
Background: A maxillary first molar with more than four canals is an interesting example of anatomic variations, especially when two of these canals are detected, with separate apical foramen in the distal root.
Sohez J Makani, Kiran Vachhani, Kailash Attur, Shoba Fernandes   +3 more
doaj  

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

MORPHOLOGICAL VARIABILITY OF PREMOLARS ROOTS

Romanian Journal of Medical and Dental Education, 2020
Aim of the study The successful endodontic therapy is due to the knowledge of the root and canal morphological variability of premolars. The aim of this study is to present this variability of number of roots/canals for the first and second premolars, both upper and lower, and to compare the results with data from literature.
Maria-Antonela Beldiman, Elena Luca, Cristina Iordache, Anca Mihaela Vițalariu, Liana Aminov   +4 more
openaire   +1 more source

Understorey fine root mass and morphology in the litter and upper soil layers of three Chinese subtropical forests

, 2016
To quantitatively assess how fine root biomass and necromass of understorey species vary in the litter and upper mineral soil layers. The method combines in situ sampling of the litter layer with sequential coring during the root growth stage in three ...
Wang, W, Hu, K, Tao, JP (reprint author), Southwest Univ, Key Lab Ecoenvironm Three Gorges Reservoir Reg, Chongqing Key Lab Plant Ecol & Resources Res Thre, Minist Educ,Sch Life Sci, Chongqing 400715, Peoples R China., Wu, XG, Liu, JC, Tao, JP   +5 more
core   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Evaluation of root-canal morphology and anatomy of maxillary second premolars using cone-beam computed tomography

مجله علمی دانشگاه علوم پزشکی کردستان, 2020
Background and Aim: Evaluation of root and canal morphology and anatomy of the teeth is essential for successful root treatment. This study aimed to evaluate the morphology and anatomy of the root canal of maxillary second premolars using the cone-beam ...
Maryam Tofangchiha, Marjan Bolbolian, Amin Ghasemi, Nahid Hemati   +3 more
doaj  

An analyser and generator for Irish inflectional morphology using finite-state transducers [PDF]

, 2002
Computational morphology is an important step in natural language processing. Finite-state techniques have been applied successfully in computational phonology and morphology to many of the world’s major languages. Celtic languages, such as Modern Irish,
Uí Dhonnchadha, Elaine
core