Results 101 to 110 of about 2,006,744 (301)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Growth of ‘M9’ apple root in five Central Europe replanted soils [PDF]

, 2014
Soil sickness is a widespread problem in replanted apple orchards with a complex symptomatology and etiology influenced by soil and climate conditions. Consequently, a conclusive technical solution is still lacking for intensive apple orchards.
Neri, Davide, Polverigiani, Serena, Kelderer, Markus, Serena Polverigiani, Davide Neri, Markus Kelderer, Kelderer, M.   +6 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Primary mandibular first molar with single root and single canal: a case report of a rare morphology.

Frontiers in Dentistry, 2014
Single rooted primary mandibular first molar is a rare developmental anomaly. Literatures reveal that failure of invagination of Hertwig's epithelial root sheath leads to this unusual root form.
Zahra Bahrololoomi, Roya Ghafourifard, Ali Asghar Soleimani   +2 more
doaj  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Morphological and biomechanical responses of Lespedeza bicolor turcz. roots to long-term phosphorus addition at high altitudes

Scientific Reports
Plant root morphology and mechanics are key determinants of slope stability. Soil phosphorus availability is typically limited in high-altitude regions subjected to engineering disturbances.
Meng Qi, Xiao Tan, Yuanyuan Song, Jiayi Yang, Yue Kong, Qingyue Liu, Hailong Sun   +6 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

root-project/root: Release v6-11/02

, 2017
<p>This is a development release. We created it to expose to users part of the enourmous amount of new functionalities which have been integrated in ROOT and will be available in ROOT 6.12/00.
Bertrand Bellenot, Pere Mato, Dario Berzano, TimurP, Stefan Roiser, Philippe Canal, Lorenzo Moneta, Olivier Couet, Fons Rademakers, Gerardo GANIS, Anders Eie, Enrico Guiraud, Xavier Valls, Andrei Gheata, ellert, Omar Zapata, Helge Voss, Danilo Piparo, Axel Naumann, Sergey Linev, Anirudha Bose, Raphael Isemann, wverkerke, CristinaCristescu, Vassil Vassilev, Matevž Tadel, Guilherme Amadio, marsupial, Paul Gessinger, wlav   +29 more
core   +1 more source