Results 101 to 110 of about 516,155 (304)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Morphology, RNase and transaminase of root protoplasts [PDF]
, 2017 RNase and transaminase activities were analysed for mechanically and enzymatically prepared protoplasts from Allium Cepa roots. The comparative analyses at three root regions show that the enzymes were less active in the protoplasts than in the cells ...
Pilet, Paul-Emile +2 more
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
A MT System from Turkmen to Turkish employing finite state and statistical methods [PDF]
, 2007 In this work, we present a MT system from Turkmen to Turkish. Our system exploits the similarity of the languages by using a modified version of direct translation method.
Adali, Esref +4 more
core +1 more source
Role of Morphology Injection in Statistical Machine Translation
, 2017 Phrase-based Statistical models are more commonly used as they perform optimally in terms of both, translation quality and complexity of the system. Hindi and in general all Indian languages are morphologically richer than English.
Bhattacharyya, Pushpak, S, Sreelekha
core +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Anatomical Evaluation of Root Apex Morphology in Frontal Maxillary Teeth [PDF]
, 2015 The success of root canal therapy is dependent on the clinician’s knowledge of root canal morphology with goal to precisely locate all canals, properly clean, shape and obturate the canal space.
Dimova, Cena +3 more
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source