Results 61 to 70 of about 511,510 (301)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Endodontic Management of Maxillary Second Molar Tooth with a Single Root and Single Canal

Case Reports in Dentistry, 2020
Comprehensive understanding of variations in the root canal morphology of a maxillary molar is useful for performing successful endodontic treatment in such cases.
Neelam Mittal, Vijay Parashar, Prasad Suresh Patel   +2 more
doaj   +1 more source

Short wind pulses consistently change the morphology of roots, but not of shoots, across young plants of different growth forms

Stress Biology, 2023
Wind is an environmental stimulus that stresses plants of all growth forms at all life-stages by influencing the development, architecture, and morphology of roots and shoots.
Johannes Heinze, Luise Werger, Michael Ogden, Thilo Heinken, Rainer Hoefgen, Ewald Weber   +5 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

MORPHOLOGICAL ALTERATIONS IN PECAN ROOTS INDUCED BY ROOT-KNOT NEMATODES [PDF]

HortScience, 1992
Root-knot nematode infection of pecan trees results in reduced growth and vigor of above ground plant parts and gall formation on roots. One-year-old roots parasitized by nematodes were collected and examined by light and scanning electron microscopy for structural anomalies.
I. Yates, D. Sparks, W.M. Powell
openaire   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Anatomical Evaluation of Root Apex Morphology in Frontal Maxillary Teeth [PDF]

, 2015
The success of root canal therapy is dependent on the clinician’s knowledge of root canal morphology with goal to precisely locate all canals, properly clean, shape and obturate the canal space.
Dimova, Cena, Kovacevska, Ivona, Papakoca, Kiro, Zlatanovska, Katerina   +3 more
core  

An implementation of Apertium based Assamese morphological analyzer

, 2015
Morphological Analysis is an important branch of linguistics for any Natural Language Processing Technology. Morphology studies the word structure and formation of word of a language. In current scenario of NLP research, morphological analysis techniques
Rahman, Mirzanur, Sarma, Shikhar Kumar
core   +1 more source

Root Pruning and Planting Depth Impact Root Morphology in Containers [PDF]

Journal of Environmental Horticulture, 2012
Increasingly, producers and consumers are realizing that roots play a major role in nursery tree quality. To remain competitive, producers need to find economically viable methods of increasing quality standards. Two studies were designed to test methods of improving root systems in a container root ball.
Edward F. Gilman, Michael Orfanedes
openaire   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source