Results 121 to 130 of about 44,303 (310)

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

PGP Attributes of Non-rhizobial Bacterial Endophytes from Root Nodules of Wild Leguminous Plant Tephrosia Purpurea (L) Pers.

Environment Conservation Journal
Global agriculture practices rely heavily on the application of fungicides, pesticides and synthetic fertilizers. Several bacterial strains were isolated from root nodules and screened for plant growth-promoting (PGP) activities.
Harshita Vashistha, Prashant Kumar, Sandeep Kumar   +2 more
doaj   +1 more source

Segmenting root systems in X-ray computed tomography images using level sets

, 2018
The segmentation of plant roots from soil and other growing media in X-ray computed tomography images is needed to effectively study the root system architecture without excavation.
Duncan, Keith E., Tabb, Amy, Topp, Christopher N.   +2 more
core   +1 more source

Reinforcing Calcium Overload via Inflammation‐Mediated Targeting to Amplify Pyroptosis and Antitumor Immunity

Advanced Science, EarlyView.
A neutrophil‐membrane‐camouflaged nanoplatform (RC@NMVs) exploits tumor inflammation to target and accumulate in tumors. Intracellular Ca2+ overload is triggered via lysosomal CaP dissolution and Ru red‐mediated Ca2+ channel blockade, synergistically inducing gasdermin‐mediated pyroptosis.
Yingying Liu, Yang Liu, Qin Fan, Jinqiao Zhang, Kexin Wen, Boyu Yuan, Xianzhou Cai, Ziliang Dong, Lianhui Wang   +8 more
wiley   +1 more source

Biochar soil amendments affect mycorrhizal colonization, root nodulation and dry matter accumulation in cowpeas (Vigna unguiculata (L.) Walp.)

Studia Universitatis Babeș-Bolyai. Biologia
There is increasing demand for renewable inputs to improve soil productivity to satisfy the ever-growing human population. Biochar as a renewable resource has attracted attention over the years as soil amendment, notable for climate change mitigation and
Ifeyinwa Monica UZOH, Keabetswe Chriscellda RAMADILE, Uchechukwu Paschal CHUKWUDI, Ozede Nicholas IGIEHON, Akinlolu Olalekan AKANMU, Olubukola Oluranti BABALOLA   +5 more
doaj   +1 more source

Inoculation of Acacia mangium with alginate beads containing selected Bradyrhizobium strains under field conditions : long-term effect on plant growth and persistence of the introduced strains in soil [PDF]

, 1994
Les essais d'innoculation faits avec 4 souches différentes de Bradyrhizobium ont un effet positif sur la croissance de Acacia mangium dont la provenance est aussi hautement significative. A long terme la souche Aust 13c a toujours un effet positif.
Diem, Hoang Gia, Galiana, Antoine, Gnahoua, Guy-Modeste, Mallet, Bernard, Poitel, Mireille, Prin, Yves   +5 more
core  

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

Morphological Studies on the Root Nodule of Leguminous Plants : (V) On the development of root nodules in Crotalaria juncea.

Japanese Journal of Crop Science, 1957
Experiments were made on morphogenesis of the root nodule of Crotalaria juncea. After the rhizobial invasion had occurred, the characteristic initial infected cells were formed in the first cortical layer adjacent to the root hair cells (Fig. 1-4). Those cells seem to become the places of rhizobial multiplication thereafter.
Tsutomu YAMASAKI, Kazumi MAEDA
openaire   +2 more sources

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source