Results 211 to 220 of about 44,303 (310)

Main factors associated with variability in the assessment of the objective response rate. A re‐analysis of the PHEREXA phase 3 clinical trial

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Local investigators (LIs) overestimate the objective response rate (ORR) in comparison to Blinded Independent Central Reviewers (BICR) in oncology. In this study, we re‐analysed data obtained in the PHEREXA trial (NCT01026142) with the following aims: i) to confirm at the single‐patient level the discrepancy observed by analysing ...
Gennaro Daniele, Tommaso Giovagnoli, Pierluigi Navarra, Cinzia Dello Russo   +3 more
wiley   +1 more source

Identification of symbiotic nitrogen fixation-modulating factors in alfalfa and mechanism elucidation of MsHHO3. [PDF]

Plant J
Wu Y, Liu Q, He F, Wang S, Ding Y, Kang J, Liang P, Yang Q, Wang X.   +8 more
europepmc   +1 more source

Exob mutants of bradyrhizobium-japonicum with reduced competitiveness for nodulation of glycine-max [PDF]

, 1993
Kosch, Kerstin, Müller, Peter, Parniske, Martin, Werner, Dietrich   +3 more
core   +1 more source

Macrophage‐targeted cerium‐tannic acid metal‐polyphenol framework nanoenzyme promotes in situ heart valves regeneration through adaptive immunomodulation

BMEMat, EarlyView.
A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song, Yunlong Wu, Xing Chen, Yafei Liu, Mengna Dong, Jiawei Shi, Xichi Wang, Nianguo Dong, Weihua Qiao, Qin Wang   +9 more
wiley   +1 more source

Pheno-morphological and biochemical characterization of root nodules and associated root nodulating bacteria from <i>Pongamia pinnata</i> (L.) Pierre in the arid regions of India. [PDF]

Front Plant Sci
Vyas V, Singh S, Choudhary S, Bhoi TK, Dey P, Saraswat A.   +5 more
europepmc   +1 more source

2D copper nanozyme patches facilitate bone regeneration via interfacial modulation of osteoclast‐osteoblast dynamics

BMEMat, EarlyView.
This study develops a nano‐enzyme patch (ezPatch) targeting bone interfaces. Utilizing ligand‐to‐metal charge transfer (LMCT) catalysis and bone‐targeting ligands on copper nanosheets, ezPatch simultaneously scavenges reactive oxygen species (ROS) and generates oxygen in situ at bone‐losing sites.
Yi Chen, Haoyue Hu, Danyang Wang, Ying Wang, Zhibang Li, Xiaoyi Liu, Yandi Zhang, Junkun Feng, Weiwei Zhao, Kai Li, Qi‐Zhi Zhong, Shaohua Ge, Jianhua Li   +12 more
wiley   +1 more source

Variations in Nodule Microbial Communities and Their Association with Root-Colonizing Arbuscular Mycorrhizal Fungi in Medicago Sativa. [PDF]

Microb Ecol
Zhang Y, Zheng C, Wang S, Zhu F.
europepmc   +1 more source

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

BMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai, Rui Zhang, Haiyin Yang, Jiyue Xing, Tianyuan Hu, Mengxi Zhu, Rui Li, Xiaoli Chen, Beibei Zhao, Yang Lan, Stefan Barth, Yuanyu Huang, Li Zhang, Mengjie Zhang, Huining He   +14 more
wiley   +1 more source

Bacterial Strains from Soybean Nodules in the Lower Volga Region Belong to a New Subspecies <i>Bradyrhizobium japonicum</i> subsp. <i>saratovii</i> subsp. nov. [PDF]

Microorganisms
Sidorin AS, Burygin GL, Fedorov AV, Katyshev AD, Krasnov YM, Tkachenko OV.   +5 more
europepmc   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source