Results 121 to 130 of about 10,849,141 (303)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Threshold autoregression with a near unit root [PDF]
unit root;autoregressive ...
Hansen,B.E., Caner,M.
core
Recursive maps of high order of convergence $m$ (say $m=2^{10}$ or $m=2^{20}$) induce certain monotone step functions from which one can filter relevant information needed to globally separate and compute the real roots of a function on a given interval $[a,b]$. The process is here called a root distiller.
openaire +2 more sources
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Breaking trend panel unit root tests [PDF]
This paper proposes Lagrange Multiplier based panel unit root tests allowing for structural breaks through simple extensions of existing group mean and combination tests. The proposed tests are more general than those previously suggested.
Pui Sun Tam, University of Macau
core
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Is there Really a Unit Root in the Inflation Rate? More Evidence from Panel Data Models [PDF]
Time series unit root evidence suggests that inflation is nonstationary. By contrast, when using more powerful panel unit root tests, Culver and Papell (1997) find that inflation is stationary.
Westerlund, Joakim, Basher, Syed A.
core
Correlation matrices of initial root tissue chemistry for pigmented first- and second-order roots, pigmented third- and fourth-order roots and combined pigmented first- , second- , third- and fourth-order roots of the root-order ...
David M. Eissenstat (388485) +7 more
core +1 more source

