Results 101 to 110 of about 10,849,141 (303)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

High-order nonlinear solver for multiple roots

Computers & Mathematics with Applications, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Neta, B., Johnson, Anthony N.
openaire   +2 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Soil environmental changes drive root decomposition under acid and nitrogen deposition in Chinese fir plantation, China

BMC Plant Biology
The decomposition of underground roots is a crucial component of soil carbon turnover and nutrient input processes. However, our understanding of how root chemistry and soil environments interact during root decomposition remains limited, and differences
Xuanran Yu, Chang Pan, Jinchi Zhang, Xingyu Zhang, Aodeng Rong, Qingguo Tong, Xiongfei Zhang, Chong Li, Hui Nie, Jingyi Zeng, Yangyang Wang, Xin Liu   +11 more
doaj   +1 more source

Optimization of Tooth Root Profile Using Bezier Curve with G2 Continuity to Reduce Bending Stress of Asymmetric Spur Gear Tooth

MATEC Web of Conferences, 2018
This research describes simple and innovative approach to reduce bending stress at tooth root of asymmetric spur gear tooth which is desire for improve high load carrying capacity.
Vaghela Priyakant, Prajapati Jagdish
doaj   +1 more source

Six-Year Nitrogen–Water Interaction Shifts the Frequency Distribution and Size Inequality of the First-Order Roots of Fraxinus mandschurica in a Mixed Mature Pinus koraiensis Forest

Frontiers in Plant Science, 2017
The variation in fine root traits in terms of size inequality at the individual root level can be identified as a strategy for adapting to the drastic changes in soil water and nutrient availabilities. The Gini and Lorenz asymmetry coefficients have been
Cunguo Wang, Zhenzhen Geng, Zhao Chen, Jiandong Li, Wei Guo, Tian-Hong Zhao, Ying Cao, Si Shen, Daming Jin, Mai-He Li   +9 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Unit Root Model Selection [PDF]

Some limit properties for information based model selection criteria are given in the context of unit root evaluation and various assumptions about initial conditions. Allowing for a nonparametric short memory component, standard information criteria are
Peter C.B. Phillips
core  

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source