Results 71 to 80 of about 26,106 (302)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Anesthetic efficacy of Oraqix® versus Hurricaine® and placebo for pain control during non-surgical periodontal treatment [PDF]

, 2013
Objectives: To evaluate the efficacy of Oraqix® during scaling and root planing (SRP) in comparison with 20% benzocaine and placebo. Study Design: 15 patients requiring 4 sessions of SRP were enrolled.
Arnabat Domínguez, Josep, Berini Aytés, Leonardo, Gay Escoda, Cosme, Mayor Subirana, Gemma, Valmaseda Castellón, E., Yagüe García, José   +5 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Pengaruh Scaling Dan Root Planing Terhadap Penurunan Clinical Attachment Level (Cal) Penderita Periodontitis (Kajian pada Wanita Menopause di Posyandu Lansia Mawar XII Kelurahan Pajang Kecamatan Laweyan) [PDF]

, 2016
Background: Women experienced periodontal disorders after menopause. The decrease of estrogen in menopausal women lead to many changes in a woman's body, one of which is a change in the decreases of gingival health and often lead to the increased ...
, drg. Edi Karyadi, M.M., Ciptaningrum, Maharatie   +1 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Efektifitas Scaling Dan Root Planing Pada Wanita Menopause Penderita Periodontitis (Tinjauan Pada Poket Periodontal Di Posyandu Lansia Mawar Xii Kelurahan Pajang Kecamatan Laweyan) [PDF]

, 2016
Background: menopause is a natural life cycle which will be a decrease in estrogen levels to almost zero. The loss of estrogen will cause symptoms that arise one of which is a problem in the oral cavity that will happen periodontal tissue damage, such as
, drg. Edi Karyadi, M.M, Nurhabibah, Gina   +1 more
core  

Photodynamic therapy in the treatment of aggressive periodontitis: a systematic review [PDF]

, 2015
Background: Aggressive periodontitis (AgP) is a severe form of periodontal diseases with rapid destruction of the supporting bone around teeth. The efficacy of PDT in suppressing periodontal pathogens may be crucial in adopting new protocols for the ...
Chatzopoulos, Georgios S., Doufexi, Aikaterini   +1 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Therapeutic Efficacy of Subgingivally Delivered Doxycycline Hyclate as an Adjunct to Non-surgical Treatment of Chronic Periodontitis

eJournal of Oral Maxillofacial Research, 2011
Objectives: Locally used doxycycline has been shown to concentrate in crevicular fluid and demonstrates a wide spectrum of activity against the periodontal pathogens.
Vikas Deo, Salman Ansari, Sunita Mandia, Manohar Bhongade   +3 more
doaj  

Aislamiento de bacterias periodontopáticas desde hemocultivos y ateromas obtenidos de pacientes con aterosclerosis y periodontitis [PDF]

, 2007
Carlos Padilla E. Laboratorio de Investigación Microbiológica, Facultad de Ciencias de la Salud, Universidad de Talca. Talca. Chile. Fono: 71-200492. Fax: 71-200439.
Descouvieres, C., Hasbun, S., Jure, G., Lobos, O., Matus, S., Padilla, C.   +5 more
core