Results 131 to 140 of about 1,634,208 (299)

Fine root morphological characteristics and biomass distribution characteristics of different artificial forests in coastal salt land and their influencing factors

Frontiers in Plant Science
To elucidate the ecological adaptations of fine root morphological traits and biomass in tree species with different life forms to coastal saline soil, five species (Robinia pseudoacacia(RP), Sapium sebiferum(SA), Salix matsudana(SM), Quercus virginiana ...
Zhibao Wang, Jing Liang, Hong Jiang, Xiangbin Gao, Shouchao Yu, Chuanjie Zhou, Yuwei Guo   +6 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Assessment of the root surface temperature during the use of intracanal agitation systems: In vitro study. [PDF]

Braz Dent J, 2023
Fontanezi BS, Bronzato JD, Mohara NT, de-Jesus-Soares A, Frozoni M.   +4 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Erratum: Biocontrol activity of nonpathogenic strains of Fusarium oxysporum: colonization on the root surface to overcome nutritional competition. [PDF]

Front Microbiol, 2023
Frontiers Production Office.
europepmc   +1 more source

Calculation of Tooth Root Bending Fatigue Life with Considering the Influence of Roughness Parameter R_a

Jixie chuandong, 2018
The stress concentration effect of surface topography plays an important role in the fatigue properties of gears. The quantitative analysis method of the effect of surface topography on gear fatigue performance is the basic work of an in-depth study of ...
He Di, Tang Jinyuan, Li Guowen, Zhou Wei
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

A statistical study of the surface accuracy of a planar truss beam [PDF]

Surface error statistics for single-layer and double-layer planar truss beams with random member-length errors were calculated using a Monte-Carlo technique in conjunction with finite-element analysis.
Fichter, W. B., Kenner, W. Scott
core   +1 more source