Results 101 to 110 of about 583,807 (299)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Quantification of root water uptake in soil using X-ray Computed Tomography and image based modelling [PDF]

open access: yes, 2017
Spatially averaged models of root-soil interactions are often used to calculate plant water uptake. Using a combination of X-ray Computed Tomography (CT) and image based modelling we tested the accuracy of this spatial averaging by directly calculating ...
Arbogast   +46 more
core   +2 more sources

Crop root system architecture in drought response

open access: yesJournal of Genetics and Genomics
Drought is a natural disaster that profoundly impacts on global agricultural production, significantly reduces crop yields, and thereby poses a severe threat to worldwide food security. Addressing the challenge of effectively improving crop drought resistance (DR) to mitigate yield loss under drought conditions is a global issue. An optimal root system
Yanjun Zhang   +4 more
openaire   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Jatropha curcas L. Root Structure and Growth in Diverse Soils

open access: yesThe Scientific World Journal, 2013
Unlike most biofuel species, Jatropha curcas has promise for use in marginal lands, but it may serve an additional role by stabilizing soils. We evaluated the growth and structural responsiveness of young J.
Ofelia Andrea Valdés-Rodríguez   +4 more
doaj   +1 more source

DDoS-Capable IoT Malwares: comparative analysis and Mirai Investigation [PDF]

open access: yes, 2018
The Internet of Things (IoT) revolution has not only carried the astonishing promise to interconnect a whole generation of traditionally “dumb” devices, but also brought to the Internet the menace of billions of badly protected and easily hackable ...
De Donno, Michele   +3 more
core   +4 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Root architecture of two sorghum varieties differ than drought stress tolerance : [Abstract, P 7.17] [PDF]

open access: yes, 2009
Root architecture of two sorghum varieties, fitted in #Durra race# and with different response in drought conditions, has been studied on hydroponic system, pot and in situ on field.
Chopart, Jean-Louis   +2 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Dynamic and Transparent Analysis of Commodity Production Systems [PDF]

open access: yes, 2010
We propose a framework that provides a programming interface to perform complex dynamic system-level analyses of deployed production systems. By leveraging hardware support for virtualization available nowadays on all commodity machines, our framework is
Fattori, Aristide   +3 more
core   +1 more source

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