Results 111 to 120 of about 5,217,878 (218)

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Unadjusted, adjusted (for age and BMI) and final regression coefficients (β) and standard errors (SEs) for breast tissue optical properties with percent density (square root transformation) for 95 pre- and 107 post-menopausal women.

, 2015
* Adjusted for age (years) and BMI (kgm-2)Unadjusted, adjusted (for age and BMI) and final regression coefficients (β) and standard errors (SEs) for breast tissue optical properties with percent density (square root transformation) for 95 pre- and 107 ...
Kristina M. Blackmore (683905), Julia A. Knight (146661), Jane Walter (683906), Lothar Lilge (683907)   +3 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Reproducibility of Three-Dimensional Density Measurements in Teeth Using Micro-Computed Tomography: An Image Acquisition Protocol

Applied Sciences
The use of micro-computed tomography (micro-CT) has become widespread in the examination of dental tissue due to its great precision in small-scale work.
Mary Huaiquin-Zúñiga, Camila Castillo-Alonso, Gabriel M. Fonseca, Sandra López-Lázaro   +3 more
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Mycorrhizal type modifies the position of exudation carbon within the root economics space

Nature Communications
The trait‑based root economics space provides a fundamental framework for understanding plant belowground adaptation to environmental change, yet it typically omits root exudation that sustains plant resource acquisition and health.
Chunhua Lv, Ying Jin, Ruihan Li, Dongli Li, Aolin Niu, Meixuan Che, Zhenghu Zhou   +6 more
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Arbuscular mycorrhizal fungi colonization facilitates nitrogen uptake in cotton under nitrogen - reduction condition

BMC Plant Biology
Background Cotton is an economically important global crop, the yield and quality of which are strongly influenced by soil nitrogen. Low nitrogen use efficiency poses an important challenge to improve cotton yield and quality.
Hushan Wang, Yijian Wang, Xiaojiao Cheng, Yunzhu He, Zihui Shen, Wangfeng Zhang, Xiaozhen Pu   +6 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source