Results 211 to 220 of about 511,358 (304)

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Multi-locus genome-wide association studies of aluminum stress indices in shoot and root traits at seedling stage in Ethiopian durum wheat (Triticum turgidum ssp. durum) genotypes. [PDF]

BMC Plant Biol
Abebe T, Gebreselassie W, Menamo TM, Mekonnen T, Mulugeta B, Tesfaye K.   +5 more
europepmc   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

Uncovering plant root traits and mechanisms that enable penetration, exploration, and exploitation of soil parent materials: a systematic review. [PDF]

Plant Soil
Chaibva P, McCloskey CS, Sizmur T, Greenfield LM, Ahmed S, Evans DL.   +5 more
europepmc   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Correction: Genetic dissection of root traits in a rice 'global MAGIC' population for candidate traits to breed for reduced methane emission. [PDF]

Front Plant Sci
Roy RK, Misra G, Sharma S, Pahi B, Khatibi SMH, Trijatmiko KR, Kim SR, Hernandez JE, Henry A, Sreenivasulu N, Diaz MGQ, Ocampo ETM, Sinha P, Kohli A.   +13 more
europepmc   +1 more source

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

Advanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang, Dongzhi Wang, Yafei Guo, Qi Zheng, Min Zhang, James Simmonds, Jian Hou, Xuemei Liu, Xuelei Lin, Xiaomin Bie, Xiansheng Zhang, Xiaohui Li, Yuan Chen, Xueyong Zhang, Cristobal Uauy, Fei Lu, Chengcai Chu, Zhixi Tian, Jun Xiao   +18 more
wiley   +1 more source

Effects of bisphenol A on root traits and rhizosphere bacteria: exploring the link between rhizosphere bacterial and root growth. [PDF]

BMC Microbiol
Yang M, Zuo S, Liu A, Zhong N, Lu X, Liu X, Jiang X, Hu T, Liu Y, Ren X, Zhou K, Wu C.   +11 more
europepmc   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

How do fine root traits of fast-growing trees promote soil organic carbon stabilization? [PDF]

Plant Soil
Rabearison TJ, Poirier V, Laganière J, DesRochers A.   +3 more
europepmc   +1 more source