Results 251 to 260 of about 2,585,835 (347)

Seeing the unseen: A novel approach to extract latent plant root traits from digital images. [PDF]

Plant Phenomics
Shoaib M, Dimech AM, Rochfort SJ, Topp C, Hayden MJ, Kant S.   +5 more
europepmc   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

Advanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao, Tong Xu, Chengyuan Wang, Chenyuan Wang, Junfeng Xie, Rui Zheng, Ke Wang, Xingzuo Jiang, Zewei Hu, Hongwei Jing, Lin Li, Tao Liu   +11 more
wiley   +1 more source

Seedling growth rate and root traits in the maize Nested Association Mapping (NAM) panel. [PDF]

BMC Res Notes
Montoya-Pimolwatana M, McClellan Maaz T, Kantar M, Muszynski M, Mileyko Y, Prasadh R, Dhungana I, Kiehl K, Ana AH, Nguyen A, Tausaga A, Godfrey A, Nitta AK, Tugade B, JadenYamagata-Santos D, Swantek E, Morrell ES, Kalaiwaa G, Juan GL, Larsen G, Ching IK, Mikasobe-Kealiinohomoku J, Araszewski J, Averion JCM, Strachan K, Torres KA, Botanes K, Wilkes KC, Rigge L, Lo M, Carr N, Brenner N, Johnson O, Malasarte RAB, Noland R, Naldini S, Santos SA, Pierce T, Halpern U, Miguel ZGP, Gan Z, Nguyen NH.   +41 more
europepmc   +1 more source

TOGR3, a Proteasome β4 Subunit, Orchestrates Sugar Homeostasis to Trade Off Growth and Thermotolerance in Rice

Advanced Science, EarlyView.
This study identifies a novel thermoregulatory mechanism in rice: TOGR3 partners with 26S proteasome subunits, including TT1, to drive thermoresponsive ubiquitin–proteasome activity, maintaining sugar homeostasis in stomatal regulation to balance growth and stress resistance.
Biyao Zhang, Xiaoyan Wu, Ting Xu, Feifei Guo, Xiaolu Shen, Cuiping Meng, Yanan Wang, Xue Han, Hong Zhao, Yongbiao Xue   +9 more
wiley   +1 more source

Integration of Genetic and Imaging Data to Detect QTL for Root Traits in Interspecific Soybean Populations. [PDF]

Int J Mol Sci
Islam MS, Lee JD, Song Q, Jo H, Kim Y.
europepmc   +1 more source

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Advanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu   +14 more
wiley   +1 more source

Evaluating the effects of biogas slurry and biochar as a partial substitute for chemical fertilizers on greenhouse tomato growth, root traits, and yield: a minimum data set approach. [PDF]

Front Plant Sci
Sa Q, Zheng J, Wang Y, Fu X, Wu Y, Liu A.   +5 more
europepmc   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Python algorithm package for automated Estimation of major legume root traits using two dimensional images. [PDF]

Sci Rep
Ghimire A, Chung YS, Jeong S, Kim Y.
europepmc   +1 more source

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

Advanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang, Jianhui Zhao, Jie Chen, Xinyi Ma, Siyun Zhou, Alexandra Noble, Rahul Kalla, Judith Wellens, Kun Liu, Evropi Theodoratou, Jack Satsangi, Xue Li   +11 more
wiley   +1 more source