Results 61 to 70 of about 119,438 (260)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

From the Ground Up: Can Root Traits Help Understand Invasion Dynamics?

Ecology and Evolution
Trait‐based comparisons of invasive and native plants have advanced our understanding of invasion mechanisms, but most focus on aboveground traits, overlooking the influence of root traits. In this mini‐review, we synthesize existing research to evaluate
Amoi Campbell, Jennifer L. Funk, Sara Kuebbing, Martin A. Nuñez, Gabriela C. Nunez‐Mir, Matthew A. McCary   +5 more
doaj   +1 more source

Flooding-adaptive root and shoot traits in rice [PDF]

Functional Plant Biology
Wetland plants, including rice (Oryza spp.), have developed multiple functional adaptive traits to survive soil flooding, partial submergence or even complete submergence. In waterlogged soils and under water, diffusion of O2 and CO2 is extremely slow with severe impacts on photosynthesis and respiration.
Chen Lin, Zhao Zhang, Xuwen Shen, Dan Liu, Ole Pedersen   +4 more
openaire   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

ROOTS OF CULTURAL AND LINGUISTIC TRAITS

The Economic Journal
Abstract This paper examines the roots of the coevolution of cultural and linguistic traits. It advances the hypothesis and establishes empirically that geographical characteristics conducive to the emergence of fundamental cultural traits triggered the evolution of complementary linguistic traits, thereby reinforcing their adaptation
Oded Galor, Ömer Özak, Assaf Sarid
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Role of secondary and putative traits for improvement of upland rice [PDF]

Electronic Journal of Plant Breeding, 2010
Even though yield under stress is the primary trait for selection in breeding programmes for drought prone environments,low heritability of yield necessitates an alternative approach such as selection for secondary and putative traits.
A.Sheeba, P.Vivekanandan, S. Banumathy, R.Manimaran and G.V.Ramasubramanian
doaj  

Characterising shoot and root system trait variability and contribution to genotypic variability in juvenile cassava (Manihot esculenta Crantz) plants

Heliyon, 2018
The development of cassava genotypes with root system traits that increase soil resource acquisition could increase yields on infertile soils but there are relatively few work that has quantified cassava root system architecture (RSA).
Michael Osei Adu, Paul Agu Asare, Elvis Asare-Bediako, Godwin Amenorpe, Frank Kwekucher Ackah, Emmanuel Afutu, Mishael Nyarko Amoah, David Oscar Yawson   +7 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Root architectural traits and yield stability in popular wheat (Triticum aestivum) varieties of India

The Indian Journal of Agricultural Sciences, 2020
The root system architecture has bearing on realizing the yield potential of genotypes. The 24 popular wheat (Triticum aestivum L.) varieties released during the last 50 years for North Western Plain Zone (NWPZ) of India were used to study root traits ...
Naresh Kumar Bainsla, Vikram Singh, Arvind Kumar, Manjeet Kumar, Rajbir Yadav, Ambrish K Sharma, Akshay K Sakhare, Ram Kumar Sharma   +7 more
doaj   +1 more source