Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Effect of harvesting time on root yield and nutritional composition of orange-fleshed sweet potato [Ipomoea batatas (L.) Lam] varieties in East Hararghe. [PDF]
HeliyonBedassa CB +4 more
europepmc +1 more source
Effects of Different Levels and Application Times of Humic Acid on Root and Leaf Yield and Yield Components of Forage Turnip (Brassica rapa L.) [PDF]
, 2005 Sebahattın Albayrak, Necdet Çamaş
openalex +1 more source
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Residue management and crop sequence effects on the yield and brown girdling root rot of canola [PDF]
, 2005 Y. K. Soon +2 more
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
EFFECTS OF PARTIAL ROOT EXCISION AT THE RE_GREENING STAGE OF WINTER WHEAT ON ROOT/SHOOT RATIO, YIELD AND WATER USE EFFICIENCY IN LOESS PLATEAU REGION, CHINA [PDF]
, 2006 MA Shou-chen +6 more
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Root Characteristics of Super High-Yield Spring Maize
ACTA AGRONOMICA SINICA, 2011 Zhang Yuqin +7 more
openaire +2 more sources