Results 91 to 100 of about 1,015,736 (307)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Properties of Estimated Characteristic Roots [PDF]

open access: yes
Estimated characteristic roots in stationary autoregressions are shown to give rather noisy information about their population equivalents. This is remarkable given the central role of the characteristic roots in the theory of autoregressive processes ...
Bent Nielsen, Heino Bohn Nielsen
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Properties of etimated characteristic roots [PDF]

open access: yes
Estimated characteristic roots in stationary autoregressions are shown to give rather noisy information about their population equivalents. This is remarkable given the central role of the characteristic roots in the theory of autoregressive processes ...
Bent Nielsen, Heino Bohn Nielsen
core  

Blak Roots [PDF]

open access: yes, 2008
[Extract] KickArts is proud to present Blak Roots, a survey exhibition of new works of art by Indigenous artists that celebrates 20 years of World Heritage in Far North Queensland.
Milledge, Russell
core   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Unit roots in macroeconomic time series: theory, implications, and evidence [PDF]

open access: yes
The theme of unit roots in macroeconomic time series has received a great amount of theoretical and applied research in the last two decades. This paper presents some of the main issues regarding unit root tests, explores some of the implications for ...
Gilberto A. Libanio
core  

CGIAR Research Program on Roots, Tubers and Bananas - Plan of Work and Budget 2020

open access: yes, 2020
The impact pathways (see Figure 1) towards the development outcomes remain relevant and, to enhance its effectiveness, the CGIAR Research Program on Roots, Tubers and Bananas (RTB) is pursuing closer coordination and better integration with other CRPs ...
CGIAR Research Program on Roots, Tubers and Bananas
core  

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