Results 271 to 280 of about 2,572,208 (344)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Integrated metabolomics and metagenomics uncover pathogenic mechanisms of Fusarium wilt and faba bean defense responses. [PDF]

NPJ Sci Food
Zheng J, Zhang C, Xiang S, Li M, Wang H, Shi K, Tondrob D, Han Y.   +7 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

AhMTP9-Mediated manganese tolerance mechanisms in peanut: integrated physiological and molecular responses of roots and leaves to Mn stress. [PDF]

BMC Plant Biol
Guo J, Zhao M, Yang S, Xue Y, Zhang R, Hu H, Liu Y.   +6 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The Tasmanian Fire Service Community Development Pilot: Evaluation of a Grass Roots Community Engagement Approach

, 2011
Mai Frandsen
openalex  

Studies on Potassium Accumulation in Detached Barley Roots (Part 3) On the Potassium Accumulation and the Oxido-Reduction States of Pyridine Nucleotides

, 1963
Hideo Ohyama, Tadaaki Kuroda, Kōichiro Honda   +2 more
openalex   +1 more source

Unearthing the mechanisms of the mycorrhizal-bacterial symbiosis in plant roots using a metatranscriptomic approach

, 2016
Gautam Naishadham
openalex   +1 more source

Specialization of the -adic polylogarithm to -th power roots of unity.

, 2003
Kenichi Bannai
openalex   +1 more source

Narrative, of a five years' expedition, against the revolted Negroes of Surinam, in Guiana, on the wild coast of South America, from the year 1772, to 1777 : elucidating the history of that country, and the description of its productions, viz. quadrupedes, birds, fishes, reptiles, trees, shrubs, fruits, & roots; with an account of the indians of Guiana, & Negroes of Guinea. By Captn. J.G. Stedman. Illustrated with 80 elegant engravings, designed from nature, by the author

John Gabriel Stedman
openalex   +2 more sources