Results 51 to 60 of about 15,372 (163)

Influence of intra‐articular injectate volume on joint surface coverage and leakage following canine elbow arthroscopy: A cadaveric study

Veterinary Surgery, EarlyView.
Abstract Objective To determine whether reduced intra‐articular (IA) injection volumes provide complete synovial surface coverage while minimizing leakage following canine elbow arthroscopy. Study design Randomized cadaveric study. Animals Forty elbow joints from 20 canine cadavers weighing >15 kg.
Erin Smith, Sarah Stark, Shelby Boyton, Wanda Gordon‐Evans   +3 more
wiley   +1 more source

Rebound Pain and Patient Satisfaction With Dexamethasone as an Adjunct for Peripheral Nerve Blocks. A Substudy Based on Two Randomised Clinical Trials

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 8, September 2026.
ABSTRACT Background Peripheral nerve blocks (PNBs) are a cornerstone in postoperative pain management, reducing pain, opioid consumption, and opioid‐related adverse effects. However, the duration of PNBs is limited and might result in rebound pain after block cessation.
Laura B. Madsen, Jakob H. Andersen, Anders K. Nørskov, Janus C. Jakobsen, Ole Mathiesen, Mathias Maagaard   +5 more
wiley   +1 more source

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2682-2692, August 2026.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup, Michel Tod, Laurent Bourguignon   +2 more
wiley   +1 more source

Intraperitoneal instillation of ropivacaine plus dexmedetomidine for pain relief after laparoscopic hysterectomy: A comparison with ropivacaine alone

Journal of Dr. NTR University of Health Sciences, 2016
Background and Aims: Intraperitoneal (IP) instillation of local anesthetics has been shown to minimize postoperative pain after laparoscopic surgeries. We compared the antinociceptive effects of IP dexmedetomidine combined with ropivacaine with that of ...
Sunil Chiruvella, Srinivasa Rao Nallam
doaj   +1 more source

Development of an ultrasound‐guided fascia iliaca compartment block programme for hip fracture analgesia in the accident and emergency department: A model from north lantau hospital

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
Abstract Background Patients with hip fracture presenting at accident and emergency department (AED) of North Lantau Hospital (NLTH) require transfer to a tertiary centre, and the repeated bed transfers involved are painful to the patients. Ultrasound‐guided fascia iliaca compartment block (FICB) is a regional anaesthetic technique for effective opioid‐
Man Ting Lau, Tin Man Hui, Oi Fung Wong, Shing Ko, Wai Ling Irene Lo, Kin Fai Khu, Sing Hing Choi, Yee Ngor Tsui, Yuen Sum Wong   +8 more
wiley   +1 more source

Hysteroscopy metroplasty for partial septate uterus: Just a matter of infertility?

International Journal of Gynecology &Obstetrics, Volume 174, Issue 2, Page 906-912, August 2026.
Abstract Objective The primary objective of this study is to assess the impact of hysteroscopic metroplasty on symptom relief, including dysmenorrhea, dyspareunia, and menstrual blood flow in women with partial uterine septa (U2a class). Additionally, the study aims to investigate potential correlations between clinical and ultrasonographic ...
Alessandro Arena, Agnese Virgilio, Camilla Franceschini, Erika Bettiol, Pierandrea De Benedetti, Roberto Sardina, Giulia Cincotta, Eugenia Mantovani, Renato Seracchioli, Paolo Casadio   +9 more
wiley   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, Volume 38, Issue 8, Page 442-452, August 2026.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Technical note on an ovine model to study biomedical implants intended for maxillofacial reconstruction

Veterinary Surgery, Volume 55, Issue 6, Page 1152-1164, August 2026.
Abstract Objective To describe a repeated‐measures model permitting evaluation of up to four implants intended for maxillofacial applications in sheep. Animals Two‐year‐old Merino wethers (n = 5). Methods A retromandibular subparotid approach was developed through anatomical study of atlases, predissected models and cadaveric experiments.
Reza Sanaei, Ayda Farhoudi, Babatunde A. Ayodele, George Dimitroulis, Christina M. Murray, Helen M. Davies, Alastair J. Sloan, Charles N. Pagel   +7 more
wiley   +1 more source

Sympathetic Overactivation Drives Neurogenic Alveolar Epithelial Pyroptosis via the PIEZO2‐ER Stress Pathway in Acute Lung Injury Following Intracerebral Hemorrhage

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
Following intracerebral hemorrhage, sympathetic overactivation drives acute lung injury via norepinephrine‐induced VPS35 upregulation. VPS35 promotes PIEZO2‐mediated calcium influx and impairs ATP2A2‐dependent ER calcium reuptake, triggering ER stress and NLRP3‐pyroptosis.
Shuai Han, Zirui Wang, Qiuyue Zheng, Feng Guo, Yinggang Xiao, Zi Wang, Tianfeng Huang, Yongxin Liang, Bingchun Yan, Ju Gao   +9 more
wiley   +1 more source

THE COSTS OF REGIONAL ANESTHESIA WITH THE USE OF LEVOBUPIVACAINE, RACEMIC BUPIVACAINE AND ROPIVACAINE

Фармакоэкономика, 2017
Background and Objective. Currently in clinical practice are widely used local anesthetics, including racemic bupivacaine, levo isomer of its levobupivacaine and structurally similar to bupivacaine levo isomer ropivacaine.
G. E. Ulrikh, A. V. Rudakova
doaj   +1 more source