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A Pulmonary Lactobacillus murinus Strain Induces Th17 and RORγt+ Regulatory T Cells and Reduces Lung Inflammation in Tuberculosis

Journal of Immunology, 2021
Key Points Lactobacillus murinus increases lung Th17 and RORγt+ Tregs in naive and infected mice. L. murinus enhances the immunosuppressive phenotype of lung Th17 and RORγt+ Tregs. L. murinus reduces lung inflammation without affecting the bacilli burden.
Lucie Bernard-Raichon, A. Colom, Sarah C. Monard, A. Namouchi, Margaux Cescato, Hugo Garnier, S. Leon-Icaza, Arnaud Métais, A. Dumas, Dan Corral, Natsinet Ghebrendrias, Pauline Guilloton, C. Vérollet, D. Hudrisier, A. Rémot, P. Langella, Muriel Thomas, C. Cougoule, O. Neyrolles, G. Lugo-Villarino   +19 more
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