Results 101 to 110 of about 24,235,259 (324)

Safety assessment of proteasome inhibitors real world adverse event analysis from the FAERS database

Scientific Reports
Proteasome inhibitor analogs (PIs) have significantly improved the degree of remission and survival rate of patients with multiple myeloma. However, serious adverse events (AEs) have hindered their clinical application.
Jinlong Huang, Miaomiao Zhang, Jingyang Lin, Xiuli Yang, Ping Huang, Xiaochun Zheng   +5 more
doaj   +1 more source

Chitosan/Gelatin Hydrogels With Hydroxyapatite/Silver Nanoparticles: A Dual Antimicrobial and Biocompatible Platform for Bone Regeneration

Journal of Applied Polymer Science, EarlyView.
Chitosan/gelatin hydrogels containing hydroxyapatite or hydroxyapatite/silver nanoparticles were developed and evaluated for bone tissue engineering applications, demonstrating biocompatibility and antimicrobial activity. ABSTRACT Bone tissue engineering demands multifunctional biomaterials capable of promoting regeneration while preventing local ...
Elisabeth Assis Martins Machado, Anne Caroline da Silva Rocha, Lívia Rodrigues de Menezes   +2 more
wiley   +1 more source

Suppressive Effects of JTE-151, a Novel Orally Available ROR<i>γ</i> Antagonist, in Experimental Models of Rheumatoid Arthritis

Biological and Pharmaceutical Bulletin
Rheumatoid arthritis (RA) is a common autoimmune disease characterized by chronic joint inflammation and cartilage damage. The main treatment goal of RA is clinical remission using various kinds of disease-modifying antirheumatic drugs (DMARDs), but there remain unmet medical needs such as the need for sufficient therapeutic efficacy, long-term safety,
Kojo Arita, Sho Otake, Kazuma Kobayashi, Hidenori Iwasaki, Yoshihisa Okamoto, Yoshiaki Katsuda, Noriko Konishi, Takayuki Yamaguchi   +7 more
openaire   +3 more sources

Curation and Community: Setting Metadata Policies at ROR

ROR’s curation model offers a unique example of how to curate PID metadata at scale through an open, responsive, and community-driven process. This session will review how the model was developed, discuss the tricky issues and decisions that ROR has ...
Gould, Maria, Buttrick, Adam
core   +1 more source

Analisis Perbandingan Pembangunan Aplikasi Web Ajax dengan Menggunakan Framework PRADO dan RoR [PDF]

, 2011
ABSTRAKSI: Perkembangan teknologi web berkembang pesat. Dibutuhkan aplikasi web yang menjamin interaksi antara client dan server sehingga lebih atraktif. Untuk itulah hadir teknik pemrograman Ajax. Ajax merupakan gabungan penggunaan HTML, DOM, javascript,
Dedi Setiawan
core  

Quantification of Sulfonated Polyacrylamides by SEC‐UV in Produced Water: Validation and Oilfield Case Study

Journal of Applied Polymer Science, EarlyView.
Size exclusion chromatography with UV–vis detection, combined with ultrasonication pretreatment, enables sensitive detection and quantification of back‐produced polymer at very low concentrations in produced water. This approach supports reliable polymer monitoring and offers a practical route to improve surveillance of polymer flooding performance ...
Eduardo José Creatto, Luis Maqueira, Daniel da Silva Vicente, Thierry Leblanc, Nathaniel Terra, Lara Arinelli, Aurora Pérez‐Gramatges   +6 more
wiley   +1 more source

Multivariate generalized mixed-effects models for screening multiple adverse drug reactions in spontaneous reporting systems

Frontiers in Pharmacology
Introduction: For assessing drug safety using spontaneous reporting system databases, quantitative measurements, such as proportional reporting rate (PRR) and reporting odds ratio (ROR), are widely employed to assess the relationship between a drug and a
Masahiko Gosho, Ryota Ishii, Tomohiro Ohigashi, Kazushi Maruo   +3 more
doaj   +1 more source

RAR‐Related Orphan Receptor Gamma (ROR‐γ) Mediates Epithelial‐Mesenchymal Transition Of Hepatocytes During Hepatic Fibrosis

Journal of Cellular Biochemistry, 2017
The epithelial‐mesenchymal transition (EMT) is involved in many different types of cellular behavior, including liver fibrosis. In this report, we studied a novel function of RAR‐related orphan receptor gamma (ROR‐γ) in hepatocyte EMT during liver ...
Sung Min Kim, Jung-Eun Choi, W. Hur, Jung-Hee Kim, Sung Woo Hong, E. B. Lee, J. Lee, Tian Zhu Li, P. Sung, S. Yoon   +9 more
semanticscholar   +1 more source

Energy production optimization by run-of-river power plants : A decision support tool for planning of RoR power systems

, 2017
In global energy scenario today, hydropower is the leading renewable source for generation of electricity. Hydropower is also considered as a clean and sustainable technology for its non-consumptive use of water resources and giving back to the river ...
Thapa Magar, Subash
core   +1 more source

Comparative and functional anatomy of masticatory muscles and bite force in opossums (Didelphimorphia, Didelphidae)

The Anatomical Record, EarlyView.
We describe the functional anatomy of masticatory muscles in nine opossums, finding a generalized anatomical pattern with differences related to skull morphology. Variation in quantitative myological data and estimated bite force was mostly related to size, and the increase in bite force supports dietary diversification associated with size increase ...
Juann A. F. H. Abreu, Diego Astúa
wiley   +1 more source