Results 41 to 50 of about 22,830 (226)
Indian Journal of Pathology and MicrobiologyBackground: Driver mutations and immunological expressions have gained importance in recent years for targeted therapies and immunotherapies of nonsmall cell lung cancer (NSCLC). Aims: This study examined the association between PD-L1 expression and ALK,
Dülger Onur, Yaylım İlhan, Öz Büge
doaj +1 more source
ROS1 demethylates the ROS1 promoter and reduces expression.
, 2015 (A) Methylation of the 5' region of ROS1 (region 1 in Fig 3) was measured in two ros1 missense mutants by bisulfite PCR. WT strains were segregating Col-0 siblings for ros1-7 and were C24 for ros1-2.
Daniela Pignatta (376799) +3 more
core +1 more source
DEMETER plays a role in DNA demethylation and disease response in somatic tissues of Arabidopsis
Epigenetics, 2019 DNA demethylases function in conjunction with DNA methyltransferases to modulate genomic DNA methylation levels in plants. The Arabidopsis genome contains four DNA demethylase genes, DEMETER (DME), REPRESSOR OF SILENCING 1 (ROS1) also known as DEMETER ...
Ulrike Schumann +7 more
doaj +1 more source
Zhongliu Fangzhi Yanjiu, 2018 Objective To construct the recombinant plasmid carrying CD74-ROS1 fusion gene, and explore its effect on migration ability of A549 cells. Methods CD74 and ROS1 genes were obtained through PCR. The CD74-ROS1 fusion gene was constructed by fusion PCR.
WU Yazhou, LI Jia, ZHANG Lei
doaj +1 more source
A Prediction Model for ROS1-Rearranged Lung Adenocarcinomas based on Histologic Features. [PDF]
PLoS ONE, 2016 AIMS:To identify the clinical and histological characteristics of ROS1-rearranged non-small-cell lung carcinomas (NSCLCs) and build a prediction model to prescreen suitable patients for molecular testing.
Jianya Zhou +8 more
doaj +1 more source
Advanced Robotics Research, EarlyView.Autonomous field robots equipped with ISFET‐based sensors enable rapid, spatially resolved soil nutrient analysis directly in the field. An automated system based on the BoniRob platform is presented for standardized on‐site extraction and measurement of key macronutrients and soil pH.
Vadim Riedel +3 more
wiley +1 more source
Advanced Intelligent Systems, EarlyView.This study presents an integrated proof‐of‐concept robotic platform for targeted delivery applications. A hybrid magnetic actuation system achieves single‐input (z) multistate stabilization (x, y, ϕ, and θ) for precise capsule transport with submillimeter positioning accuracy.
Sejun Park +6 more
wiley +1 more source
, 2017 ROS1 is a receptor tyrosine kinase that has recently been shown to undergo gene rearrangements in~1%–2% of non-small cell lung carcinoma (NSCLC) and in a variety of other tumours including cholangiocarcinoma, gastric carcinoma, colorectal carcinoma and ...
Prodipto Pal, Zanobia Khan
core +1 more source
Progress of non-small-cell lung cancer with ROS1 rearrangement
Frontiers in Molecular Biosciences, 2023 ROS1 rearrangement is found in 0.9%–2.6% of people with non-small-cell lung cancers (NSCLCs). Tyrosine kinase inhibitors (TKIs) target ROS1 and can block tumor growth and provide clinical benefits to patients. This review summarizes the current knowledge
Xin Yang +4 more
doaj +1 more source
Mouse model for ROS1-rearranged lung cancer. [PDF]
, 2013 Genetic rearrangement of the ROS1 receptor tyrosine kinase was recently identified as a distinct molecular signature for human non-small cell lung cancer (NSCLC).
Yasushi Totoki +26 more
core +1 more source