Results 71 to 80 of about 22,830 (226)
The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors
Medicinal Research Reviews, EarlyView.ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti +6 more
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Lack of ROS1 Gene Rearrangement in Glioblastoma Multiforme [PDF]
, 2015 Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor, and the prognosis remains poor. Rearrangement of ROS1 gene, which was shown to have an oncogenic potential, was previously discovered in GBM cell lines.
임선민 +3 more
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Therapeutics and Clinical Risk Management, 2020 Shinkichi Takamori, 1 Takashi Seto, 1 Mikako Jinnouchi, 2 Taro Oba, 1 Masafumi Yamaguchi, 1 Mitsuhiro Takenoyama 1 1Department of Thoracic Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka 811-1395, Japan; 2Department of Radiology,
Takamori S +5 more
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The epigenetic landscape of plant defense: Unlocking nature's toolkit for new plant protection
New Plant Protection, EarlyView.This review examines how epigenetic mechanisms regulate plant immune gene activation, repression, and priming, then links these natural regulatory layers to emerging epigenetic editing, discussing their potential for precise, heritable crop protection and the challenges.
Xuexia Liu, Zhenhui Zhong
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Comparison of histological parameters among ROS1-positive and ROS1-negative NSCLCs.
, 2016 Comparison of histological parameters among ROS1-positive and ROS1-negative NSCLCs.
Jing Zheng (65946) +8 more
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Precision Medical Sciences, EarlyView.The translational pipeline of precision medicine in clinical oncology. Schematic overview of the individualized cancer care workflow. (1) Input: Patient samples undergo multi‐omic profiling via NGS, single‐cell diagnostics, spatial maps, and epigenetic sequencing.
Asif Jan +3 more
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Clinicopathological analysis of ROS1 gene alterations and immunohistochemistry screening for ROS1 gene rearrangement in non-small cell lung cancer [PDF]
, 2015 학위논문 (박사)-- 서울대학교 대학원 : 의학과 병리학전공, 2015. 8. 정진행.Introduction: ROS1 rearrangement, found in a subset of lung cancers, have therapeutic significance, as ROS1-rearranged tumors are sensitive to ALK kinase inhibitors.
김연
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MET18 physically associates with ROS1.
, 2015 A. Mass spectrometric analysis of MET18 affinity purification. Selected unique proteins co-purified from MET18-3FH transgenic plants but not from wild-type are indicated. B.Y2H assays of protein interactions between ROS1, MET18 and AE7.
Cheng-Guo Duan (817130) +11 more
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EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis [PDF]
, 2017 [[abstract]]Current anti-epidermal growth factor receptor (EGFR) therapy for oral cancer does not provide satisfactory efficacy due to drug resistance or reduced EGFR level.
Shih, CH;Chang, YJ;Huang, WC;Jang, TH;Kung, HJ;Wang, WC;Yang, MH;Lin, MC;Huang, SF;Chou, SW;Chang, E;Chiu, H;Shieh, TY;Chen, YJ;Wang, LH;Chen, L
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, 2015 (A) Immunohistochemical staining of ROS1 showing negative immunoreactivity (B) ROS1 break-apart fluorescent in situ hybridization showing negativity for ROS1 rearrangement.
Frank Policht (795308) +8 more
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