Results 91 to 100 of about 38,562 (318)

Dysregulated proteolytic cascades in Netherton syndrome: from molecular pathology to preclinical drug testing

The Journal of Pathology, EarlyView.
Abstract Netherton syndrome (NS) is a rare, severe, and often life‐threatening disease for which current therapeutic approaches are limited and show variable effectiveness. NS is characterized by excessive epidermal desquamation that results in a highly defective epidermal barrier, constitutive skin inflammation, allergies, and hair abnormalities.
Eleni Zingkou, Evangelos Bisyris, Georgios Pampalakis, Georgia Sotiropoulou   +3 more
wiley   +1 more source

Retrospective Study : Rosacea Profile

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2016
Background: Rosacea is a chronic skin disorder which characterized by erythema of the central face that has persisted for months. Primary features of rosacea include flushing, papules, pustules, and telangiectatic.
Shakti Indraprasta, Trisniartami Setyaningrum   +1 more
doaj   +1 more source

Challenges in the management of pediatric blepharokeratoconjunctivis / ocular rosacea [PDF]

, 2016
Introduction: Childhood blepharokeratoconjunctivitis is a common lid margin inflammation with secondary ocular surface disease. Its etiology is unclear and there are no randomized controlled trials to support the superiority of any treatment option ...
Dahlmann-Noor, A, Daniel, MC, Hingorani, M, O’Gallagher, M, Tuft, S   +4 more
core   +1 more source

Therapeutic strategies focusing on immune dysregulation and neuroinflammation in rosacea

Frontiers in Immunology
Rosacea is a complex inflammatory condition characterized by papulopustular lesions and erythema on the central face for which there is no cure.
Kuan-Yi Tu, C. Jung, Yi-Hsien Shih, Anne Lynn S. Chang   +3 more
semanticscholar   +1 more source

Mast cell stabilization: new mechanism underlying the therapeutic effect of intense pulsed light on rosacea

Inflammation Research, 2022
Background Rosacea, a chronic inflammatory disorder of the facial skin, is effectively treated by intense pulsed light (IPL). Objective To explore the potential molecular mechanism underlying the photobiomodulation effect of IPL for rosacea treatment ...
Peiyu Jiang, Yunyi Liu, Jiawen Zhang, Yixuan Liu, Min Li, Meng Tao, Yue Zhang, Zongxiang Tang, Wentao Liu, Yang Xu   +9 more
semanticscholar   +1 more source

Nanoemulsions for Skin Delivery of Essential Oils: A Systematic Review

Phytotherapy Research, EarlyView.
ABSTRACT Essential oils (EOs) are recognized for their multiple health benefits. However, their high volatility, low stability, and limited water solubility limit their effective application. This systematic review aims to assess the use of nanoemulsions as delivery systems for the topical administration of EOs, highlighting their efficacy, safety, and
Thais Leticia Moreira da Silva, Anna Claudia Morais de Oliveira Capote, Flávio Luís Beltrame, Priscileila Colerato Ferrari   +3 more
wiley   +1 more source

Rosacea, Germs, and Bowels: A Review on Gastrointestinal Comorbidities and Gut–Skin Axis of Rosacea

Advances in Therapy, 2021
Rosacea is a chronic inflammatory disease with complicated pathophysiology that involves genetic and environmental elements and dysregulation of innate and adaptive immunity, neurovascular responses, microbiome colonization or infection, resulting in ...
Fang-Ying Wang, C. Chi
semanticscholar   +1 more source

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

Rare Metals, EarlyView.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan, Shengjie Xue, Junyi Yin, Shaolei Wang, Yunlei Zhou, Jieyue Liao   +5 more
wiley   +1 more source

Rosaatsea ja perioraalne dermatiit [PDF]

, 2007
Rosaatsea on sage ebaselge põhjusega krooniline nahahaigus, mis haarab näo tsentraalseid alasid. Diagnoosiks on vajalik ühe või mitme primaarse tunnuse olemasolu: õhetus, transitoorne erüteem, paapulid ja pustulid või teleangiektaasiad.
Abram, Kristi, Oona, Marje, Silm, Helgi
core   +2 more sources

Perspectives on rosacea patient characteristics and quality of life using baseline data from a phase 3 clinical study conducted in Japan

Journal of dermatology (Print), 2022
There is a lack of contemporary data on rosacea originating in Japan. Using baseline data from a randomized, phase 3 study of 130 Japanese patients with rosacea treated with metronidazole gel (0.75%) or vehicle, the authors evaluated demographic and ...
K. Yamasaki, Yoshiki Miyachi
semanticscholar   +1 more source