Results 11 to 20 of about 23,468 (228)

Imperatorin Mitigates Rosacea-Like Inflammation by Modulating the Crosstalk Between JNK1 and STAT1. [PDF]

open access: yesFASEB J
IMP treatment disrupts the interaction between JNK1 and STAT1, thereby attenuating STAT1 activity. This interference subsequently diminishes the phosphorylation and nuclear translocation of STAT1, which ultimately results in a reduced production of inflammatory cytokines and chemokines.
Wang X, Zhu Z.
europepmc   +2 more sources

TLR7 promotes skin inflammation via activating NFκB-mTORC1 axis in rosacea [PDF]

open access: yesPeerJ, 2023
Rosacea is a chronic inflammatory skin disease originated from damaged skin barrier and innate/adaptive immune dysregulation. Toll-like receptors (TLRs) sense injured skin and initiate downstream inflammatory and immune responses, whose role in rosacea ...
Yaqun Huang   +12 more
doaj   +2 more sources

EGCG identified as an autophagy inducer for rosacea therapy

open access: yesFrontiers in Pharmacology, 2023
Background: Rosacea is a common facial skin inflammatory disease featured by hyperactivation of mTORC1 signaling in the epidermis. Due to unclear pathogenesis, the effective treatment options for rosacea remain limited.Methods: Weighted gene co ...
Lei Zhou   +20 more
doaj   +1 more source

Oral JAK Inhibitors as a Promising Therapeutic Strategy for Refractory Rosacea: A Systematic Review and Meta-Analysis. [PDF]

open access: yesJ Cosmet Dermatol
ABSTRACT Background Rosacea is a chronic inflammatory dermatosis. While standard therapies exist, managing refractory subtypes remains a therapeutic challenge. Oral Janus kinase (JAK) inhibitors have emerged as potential alternatives, but systematic evidence is lacking. Aims To evaluate the efficacy and safety of oral JAK inhibitors for rosacea through
Peng Y, Sun M, Chen J, Huang X, Zhang F.
europepmc   +2 more sources

Ocular rosacea and corneal perforation: A rare case report

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth, 2021
Acne rosacea is a chronic skin condition with exacerbations and remissions, which requires long-term therapy to maintain symptomatic control.
Sujit Das, B Pradeep, Chhanda Mandal
doaj   +1 more source

Tetracycline Actions Relevant to Rosacea Treatment [PDF]

open access: yes, 2009
Until today, the pathogenesis of rosacea is not known in detail. Yet in recent years evidence has been accumulating that rosacea with its common symptoms such as inflammatory lesions, erythema, telangiectasia, phymatous changes, and ocular symptoms is of
Korting, Hans Christian, Schöllmann, C.
core   +1 more source

Rosacea [PDF]

open access: yesAAOHN Journal, 2007
Rosacea rarely resolves on its own. Occupational health nurses can help employees seek early treatment.
openaire   +2 more sources

A case of Scalp Rosacea treated with low dose doxycycline and probiotic therapy and literature review on therapeutic options [PDF]

open access: yes, 2016
Rosacea is a common chronic inflammatory disorder showing a wide range of clinical features such as telangiectasia, erythema, papules, and pustules primarily involving the central part of face (forehead, cheeks and nose) although extra facial ...
Cardone, Michele   +6 more
core   +1 more source

Mediation roles of neutrophils and high-density lipoprotein (HDL) on the relationship between HLA-DQB1 and rosacea

open access: yesAnnals of Medicine, 2022
Background Though the previous genome-wide association studies found the association between HLA alleles and rosacea in the European populations, the data is lacking among the Asians. Moreover, neutrophils are important in the immune-related mechanism of
Wenqin Xiao   +7 more
doaj   +1 more source

Relationship between Helicobacter pylori and Rosacea: review and discussion

open access: yesBMC Infectious Diseases, 2018
Background Rosacea is an inflammatory disease affecting the central part of face characterized by persistent or recurrent episodes of erythema, papules, pustules and telangiectasias of unknown etiology. Helicobacter pylori (H.
Xingzhe Yang
doaj   +1 more source

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