Results 11 to 20 of about 35,642 (325)

A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea

EMBO Molecular Medicine, 2021
Rosacea is a chronic inflammatory skin disorder whose pathogenesis is unclear. Here, several lines of evidence were provided to demonstrate that mTORC1 signaling is hyperactivated in the skin, especially in the epidermis, of both rosacea patients and a ...
Zhili Deng, Mengting Chen, Yingzi Liu, San Xu, Yuyan Ouyang, Wei Shi, Dan Jian, Ben Wang, Fangfen Liu, Jinmao Li, Qian Shi, Qinqin Peng, Ke Sha, Wenqin Xiao, Tangxiele Liu, Yiya Zhang, Hongbing Zhang, Qian Wang, Lunquan Sun, Hongfu Xie, Ji Li   +20 more
doaj   +2 more sources

A Case–Control Study Examining the Differences in Vitamin D Levels Between Individuals With Rosacea and Healthy Individuals [PDF]

Journal of Cosmetic Dermatology, Volume 24, Issue 6, June 2025.
ABSTRACT Background Rosacea is an inflammatory and chronic skin condition that may be affected by many factors. The purpose of this study is to compare the level of vitamin D in two groups of cases (suffering from rosacea) and controls (healthy).
Gita Faghihi, Fatemeh Mohaghegh, Mohammad Shoushtarizadeh, Nazila Poostiyan, Sayed Mohsen Hosseini, Arian Khosravi   +5 more
wiley   +2 more sources

Acne and Rosacea [PDF]

Dermatology and Therapy, 2017
Acne, one of the most common skin diseases, affects approximately 85% of the adolescent population, and occurs most prominently at skin sites with a high density of sebaceous glands such as the face, back, and chest. Although often considered a disease of teenagers, acne is occurring at an increasingly early age.
Picardo, Mauro, Eichenfield, Lawrence F, Tan, Jerry   +2 more
openaire   +6 more sources

A Novel Convolutional Neural Network for the Diagnosis and Classification of Rosacea: Usability Study

JMIR Medical Informatics, 2021
BackgroundRosacea is a chronic inflammatory disease with variable clinical presentations, including transient flushing, fixed erythema, papules, pustules, and phymatous changes on the central face. Owing to the diversity in the clinical manifestations of
Zhao, Zhixiang, Wu, Che-Ming, Zhang, Shuping, He, Fanping, Liu, Fangfen, Wang, Ben, Huang, Yingxue, Shi, Wei, Jian, Dan, Xie, Hongfu, Yeh, Chao-Yuan, Li, Ji   +11 more
doaj   +2 more sources

Therapeutic Modulation of Demodex Density via Isotretinoin: Insights From a Prospective Dermatological Investigation [PDF]

Journal of Cosmetic Dermatology, Volume 24, Issue 6, June 2025.
ABSTRACT Aim Demodex spp. are ectoparasites that reside in pilosebaceous units, particularly on the face where sebum secretion is prominent. The sebum‐reducing effects of isotretinoin play a crucial role in the management of acne vulgaris and rosacea. This study aims to assess the effect of isotretinoin on Demodex density in patients with acne vulgaris
Ahmed Muayad Jirjees Chakmakchi, Emine Tugba Alatas, Aslan Yurekli, Ceyda Tetik Aydoğdu, Suzan Demir Pektas   +4 more
wiley   +2 more sources

Multi-Transcriptomic Analysis and Experimental Validation Implicate a Central Role of STAT3 in Skin Barrier Dysfunction Induced Aggravation of Rosacea

Journal of Inflammation Research, 2022
Yaling Wang,1,2 Ben Wang,1,2 Yingxue Huang,1 Yangfan Li,1,2 Sha Yan,1 Hongfu Xie,1– 3 Yiya Zhang,1– 3 Ji Li1– 3 1Department of Dermatology, Xiangya Hospital, Central South University, Changsha, People’s Republic of China; 2Hunan Key Laboratory of Aging ...
Wang Y, Wang B, Huang Y, Li Y, Yan S, Xie H, Zhang Y, Li J   +7 more
doaj   +2 more sources

Submicrobial Dosing of Antibiotics in Dermatology: A Survey of Real World Practice Patterns [PDF]

Australas J Dermatol
Australasian Journal of Dermatology, Volume 66, Issue 4, Page e241-e242, June 2025.
Henry Zou, Elham Tabatabaei, Johe Houston Johnson, Steven Daveluy   +3 more
wiley   +2 more sources

Rosacea in childhood and adolescence: A review [PDF]

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 6, Page 684-691, June 2025.
Summary Despite presenting with similar symptoms, triggers, and progression patterns as adults, rosacea in children and adolescents is frequently overlooked as a primary differential diagnosis. However, initial manifestations of classic clinical types can be observed from infancy onwards.
Sören Korsing, Karola Stieler, Uwe Pleyer, Ulrike Blume‐Peytavi, Annika Vogt   +4 more
wiley   +2 more sources

Recent advances in understanding and managing rosacea [version 1; referees: 3 approved]

F1000Research, 2018
Rosacea is a common chronic inflammatory skin disease of the central facial skin and is of unknown origin. Currently, two classifications of rosacea exist that are based on either “preformed” clinical subtypes (erythematotelangiectatic, papulopustular ...
Joerg Buddenkotte, Martin Steinhoff
doaj   +2 more sources

Skin Improvement in Japanese Patients With Inflammatory Dermatologic Conditions Using the Injectable Hyaluronic Acid VYC‐12 [PDF]

Journal of Cosmetic Dermatology, Volume 24, Issue 6, June 2025.
ABSTRACT Background Many skin disorders of the face have an inflammatory element, including atopic dermatitis, acne vulgaris, and rosacea. VYC‐12 is an injectable hyaluronic acid product with well‐established hydrating effects and potential anti‐inflammatory benefits.
Chiharu Watanabe
wiley   +2 more sources