Results 11 to 20 of about 23,468 (228)
Imperatorin Mitigates Rosacea-Like Inflammation by Modulating the Crosstalk Between JNK1 and STAT1. [PDF]
IMP treatment disrupts the interaction between JNK1 and STAT1, thereby attenuating STAT1 activity. This interference subsequently diminishes the phosphorylation and nuclear translocation of STAT1, which ultimately results in a reduced production of inflammatory cytokines and chemokines.
Wang X, Zhu Z.
europepmc +2 more sources
TLR7 promotes skin inflammation via activating NFκB-mTORC1 axis in rosacea [PDF]
Rosacea is a chronic inflammatory skin disease originated from damaged skin barrier and innate/adaptive immune dysregulation. Toll-like receptors (TLRs) sense injured skin and initiate downstream inflammatory and immune responses, whose role in rosacea ...
Yaqun Huang +12 more
doaj +2 more sources
EGCG identified as an autophagy inducer for rosacea therapy
Background: Rosacea is a common facial skin inflammatory disease featured by hyperactivation of mTORC1 signaling in the epidermis. Due to unclear pathogenesis, the effective treatment options for rosacea remain limited.Methods: Weighted gene co ...
Lei Zhou +20 more
doaj +1 more source
Oral JAK Inhibitors as a Promising Therapeutic Strategy for Refractory Rosacea: A Systematic Review and Meta-Analysis. [PDF]
ABSTRACT Background Rosacea is a chronic inflammatory dermatosis. While standard therapies exist, managing refractory subtypes remains a therapeutic challenge. Oral Janus kinase (JAK) inhibitors have emerged as potential alternatives, but systematic evidence is lacking. Aims To evaluate the efficacy and safety of oral JAK inhibitors for rosacea through
Peng Y, Sun M, Chen J, Huang X, Zhang F.
europepmc +2 more sources
Ocular rosacea and corneal perforation: A rare case report
Acne rosacea is a chronic skin condition with exacerbations and remissions, which requires long-term therapy to maintain symptomatic control.
Sujit Das, B Pradeep, Chhanda Mandal
doaj +1 more source
Tetracycline Actions Relevant to Rosacea Treatment [PDF]
Until today, the pathogenesis of rosacea is not known in detail. Yet in recent years evidence has been accumulating that rosacea with its common symptoms such as inflammatory lesions, erythema, telangiectasia, phymatous changes, and ocular symptoms is of
Korting, Hans Christian, Schöllmann, C.
core +1 more source
Rosacea rarely resolves on its own. Occupational health nurses can help employees seek early treatment.
openaire +2 more sources
A case of Scalp Rosacea treated with low dose doxycycline and probiotic therapy and literature review on therapeutic options [PDF]
Rosacea is a common chronic inflammatory disorder showing a wide range of clinical features such as telangiectasia, erythema, papules, and pustules primarily involving the central part of face (forehead, cheeks and nose) although extra facial ...
Cardone, Michele +6 more
core +1 more source
Background Though the previous genome-wide association studies found the association between HLA alleles and rosacea in the European populations, the data is lacking among the Asians. Moreover, neutrophils are important in the immune-related mechanism of
Wenqin Xiao +7 more
doaj +1 more source
Relationship between Helicobacter pylori and Rosacea: review and discussion
Background Rosacea is an inflammatory disease affecting the central part of face characterized by persistent or recurrent episodes of erythema, papules, pustules and telangiectasias of unknown etiology. Helicobacter pylori (H.
Xingzhe Yang
doaj +1 more source

