TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes. [PDF]
A diverse environment challenges skin to maintain temperature, hydration, and electrolyte balance while also maintaining normal immunological function. Rosacea is a common skin disease that manifests unique inflammatory responses to normal environmental ...
Kenshi Yamasaki+45 more
core +3 more sources
Multidisciplinary Consideration of Potential Pathophysiologic Mechanisms of Paradoxical Erythema with Topical Brimonidine Therapy. [PDF]
Rosacea is a chronic inflammatory disease with transient and non-transient redness as key characteristics. Brimonidine is a selective α2-adrenergic receptor (AR) agonist approved for persistent facial erythema of rosacea based on significant efficacy and
Detmar, Michael+6 more
core +2 more sources
A case of Scalp Rosacea treated with low dose doxycycline and probiotic therapy and literature review on therapeutic options [PDF]
Rosacea is a common chronic inflammatory disorder showing a wide range of clinical features such as telangiectasia, erythema, papules, and pustules primarily involving the central part of face (forehead, cheeks and nose) although extra facial ...
Cardone, Michele+6 more
core +1 more source
Interventions for Rosacea [PDF]
Which interventions are associated with highest efficacy and fewest adverse events for treating rosacea?There is high-quality evidence that topical brimonidine, azelaic acid, and ivermectin, as well as oral doxycycline and isotretinoin, are associated with improvements in rosacea.
Zuuren, E.J. van, Fedorowicz, Z.
openaire +8 more sources
Relationship between Helicobacter pylori and Rosacea: review and discussion
Background Rosacea is an inflammatory disease affecting the central part of face characterized by persistent or recurrent episodes of erythema, papules, pustules and telangiectasias of unknown etiology. Helicobacter pylori (H.
Xingzhe Yang
doaj +1 more source
Use of an alternative method to evaluate erythema severity in a clinical trial: difference in vehicle response with evaluation of baseline and postdose photographs for effect of oxymetazoline cream 1·0% for persistent erythema of rosacea in a phase IV study. [PDF]
BackgroundOnce-daily topical oxymetazoline cream 1·0% significantly reduced persistent facial erythema of rosacea in trials requiring live, static patient assessments.ObjectivesTo evaluate critically the methodology of clinical trials that require live ...
Alvandi, N+10 more
core +1 more source
The article presents results of examination of 144 patients, including 64 patients with rosacea in combination with chronic opisthorchiasis (group 1) and 80 patients with rosacea without opistorchiasis (group 2).
M. L. Aripova
doaj +1 more source
Antimicrobial Peptides and Skin: A Paradigm of Translational Medicine [PDF]
Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Albiol Matanic VC+106 more
core +1 more source
Effectiveness of VISIA system in evaluating the severity of rosacea
Rosacea is a facial chronic inflammatory skin disease with almost 5.5% prevalence. Although there are various scales of rosacea, they are objective and discordant among different dermatologists.
Yunlong Pan+3 more
semanticscholar +1 more source
The Modern Approach To The Complex Therapy Of Demodicosis [PDF]
Demodicosis is one of the most common diseases of the skin. Despite the large number of scientific publications on this issue the question of the etiology and pathogenesis of this disease still remains unresolved and the development of more effective ...
Revenko, Z. (Zhanetta)
core +3 more sources