Results 71 to 80 of about 38,562 (318)

Current views on pathogenesis of rosacea

Journal of Education, Health and Sport, 2023
Rosacea is a chronic inflammatory disease that usually affects the central part of the face. The primary symptoms include facial flushing, persistent erythema, telangiectasia,  inflammatory pustules and papules.
Iga, Borys Bondos, Robert Kochan, Patryk Barczuk, Sebastian Bara, Jędrzej Dzięgielewski, Kacper Bączek, Jan Barć, Elżbieta Gałajda, Jacek Antonik   +9 more
doaj   +1 more source

Rosacea

Actas Dermo-Sifiliográficas (English Edition), 2008
Rosacea is a chronic inflammatory skin disease appearing in the central area of the face of middle-aged patients. It is characterized by flushing, permanent erythema, telangiectasia, papules, pustules, and the absence of comedones. Its underlying pathophysiological mechanisms are not completely understood, although a number of hypotheses point to ...
D, Barco, A, Alomar
openaire   +2 more sources

A rosacea cután és oculáris megjelenési formái [PDF]

, 2018
L
Baltás, Eszter, Skribek, Ákos, Sohár, Nicolette, Töröcsik, Dániel   +3 more
core   +1 more source

Signaling pathways and targeted therapy for rosacea

Frontiers in Immunology
Rosacea is a chronic skin inflammatory disease with a global prevalence ranging from 1% to 20%. It is characterized by facial erythema, telangiectasia, papules, pustules, and ocular manifestations. Its pathogenesis involves a complex interplay of genetic,
Fengjuan Yang, Lian Wang, Deyu Song, Lu Zhang, Xiaoyun Wang, Dan Du, Xian Jiang   +6 more
semanticscholar   +1 more source

Influence of the sebaceous gland density on the stratum corneum lipidome [PDF]

, 2018
The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively.
Camera, Emanuela, Kozul, Nina, Ludovici, Matteo, Materazzi, Stefano, Picardo, Mauro, Risoluti, Roberta   +5 more
core   +1 more source

OPN promotes pro-inflammatory cytokine expression via ERK/JNK pathway and M1 macrophage polarization in Rosacea

Frontiers in Immunology
Rosacea is a chronic inflammatory dermatosis that involves dysregulation of innate and adaptive immune systems. Osteopontin (OPN) is a phosphorylated glycoprotein produced by a broad range of immune cells such as macrophages, keratinocytes, and T cells ...
Siyi Tang, Hao Hu, Manhui Li, Kaoyuan Zhang, Qi Wu, Xiaojuan Liu, Lin Wu, Bo Yu, Xiao-Fan Chen   +8 more
semanticscholar   +1 more source

Exploring the Association Between Rosacea and Parkinson Disease:A Danish Nationwide Cohort Study [PDF]

, 2016
Importance: The pathogenesis of rosacea is unclear, but increased matrix metalloproteinase target tissue activity appears to play an important role. Parkinson disease and other neurodegenerative disorders also display increased matrix metalloproteinase ...
Egeberg, Alexander, Gislason, Gunnar H, Hansen, Peter Riis, Thyssen, Jacob P   +3 more
core   +1 more source

Diabetes mellitus and necrotizing fasciitis – a deadly combination; case report [PDF]

, 2020
Necrotizing fasciitis is a rapidly destructive affliction of soft tissues, with a mortality rate that may reach 73% of the cases. It is characterized by a progressive inflammation and extended necrosis of the subcutaneous tissue and the fascia ...
Andronache, Liliana Florina, Bica, Cristina, Gherghiceanu, Florentina, Mazilu, Laura, Moroianu, Lavinia Alexandra, Paunica, Ioana, Sandu, Camelia, Suceveanu, Andra Iulia, Toma, Alexandra   +8 more
core   +3 more sources

Tofacitinib for the treatment of erythematotelangiectatic and papulopustular rosacea: A retrospective case series

Dermatologic Therapy, 2022
Rosacea is a chronic inflammatory skin disease characterized by facial erythema, papules, pustules, telangiectasia, and flushing. The Janus kinase (JAK) signal transducer and activator of transcription (STAT) pathway appears to play a role in the ...
Yan-hong Sun, X. Man, X. Xuan, Chang-Zheng Huang, Ying Shen, L. Lao   +5 more
semanticscholar   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source