Results 41 to 50 of about 3,050,600 (310)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Podocyturia an emerging biomarker for kidney injury

BMC Nephrology
Podocyte injury is an established hallmark of kidney disease progression. Podocyte loss is a widely proven hypothesis to explain, in part, glomerular damage.
Charbel Hanna, Hady El Etry, Maroun Ibrahim, Lynn Khalife, Sola Aoun Bahous, Wissam H. Faour   +5 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A highly sensitive Anti-Müllerian hormone test as a promising tool for follicle growth prediction in primary ovarian insufficiency patients

Scientific Reports
Primary ovarian insufficiency (POI) patients often require prolonged stimulation for follicular growth. Anti-Müllerian hormone (AMH), produced by granulosa cells of early-stage follicles, is a potential a biomarker for predicting follicular development ...
Zijia Guo, Bunpei Ishizuka, Atsuo Itakura, Kazuhiro Kawamura   +3 more
doaj   +1 more source

Analysis of the behaviour of the clients assisted and sales variables in the different phases of the product life cycle [PDF]

European Journal of Management and Business Economics, 2018
Purpose - The Bass model was created to analyse the product life cycle (PLC) in order to help sales and marketing departments in their business decision making. The purpose of this paper is to analyse the diferences between the clients assisted and sales
Aida Galiano, Vicente Rodríguez, Manuela Saco   +2 more
doaj   +1 more source

Marry & Burn by Rachel Rose [PDF]

, 2016
Review of Rachel Rose\u27s Marry ...
Creed, Carolyn J
core   +1 more source

Synthesizing attractors of Hindmarsh-Rose neuronal systems

, 2010
In this paper a periodic parameter switching scheme is applied to the Hindmarsh-Rose neuronal system to synthesize certain attractors. Results show numerically, via computer graphic simulations, that the obtained synthesized attractor belongs to the ...
A.L. Hodgkin, A.M. Stuart, A.V. Holden, B. Coombes, C. Foias, D. He, E. Ott, H. Sabbagh, J. Ma, J. Milnor, J.L. Hindmarsh, J.M. Gonzalez-Miranda, J.M. Gonzalez-Miranda, L. Kapitanski, M. Hirsch, M.-F. Danca, M.-F. Danca, M.-F. Danca, M.W. Hirsch, Marius-F. Danca, N. Corson, Qingyun Wang, S. Reinker, S.Q. Ma, T.R. Chay, Y.H. Zheng   +25 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Morphological characteristics of roses cut flower after vase life [PDF]

Agroznanje, 2016
Investigation was conducted under controlled conditions in the laboratory for plant production at the Faculty of Agriculture in Osijek. The cut roses used in the study were "Red Naomi".
Kraljičak Jasna, Parađiković Nada, Tkalec Monika   +2 more
doaj   +1 more source