Results 241 to 250 of about 2,065,845 (331)

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

open access: yesFood Frontiers, EarlyView.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima   +15 more
wiley   +1 more source

Future Range Shifts and Diversity Patterns of Antarctic Lecideoid Lichens Under Climate Change Scenarios

open access: yesGlobal Change Biology Communications, EarlyView.
Modeling of current and future spatial distribution of Antarctic lecideoid lichens shows that warming will strongly increase the potential habitat. Under three climate‐change scenarios, most fungal and algal partners are projected to expand inland. Overall, climate change drives widespread range shifts and promotes colonization of interior Antarctica ...
Anna Götz   +6 more
wiley   +1 more source

Connecting the Dots: Systems Thinking Highlights the Role of the Environment Sector in One Health Operationalization

open access: yesGlobal Challenges, EarlyView.
This perspective highlights the need for a systems thinking approach in One Health to holistically address zoonotic disease prevention, and to strengthen connections with the environment sector for global pandemic preparedness. Abstract With One Health (OH) encompassing a holistic view of the interrelated health of humans, animals and environment ...
Alana Hansen   +3 more
wiley   +1 more source

Rare Structural Variants Uncovered by Optical Genome Mapping in Multisystem Inflammatory Syndrome in Children (MIS‐C)

open access: yesAdvanced Genetics, EarlyView.
This study applies optical genome mapping (OGM) to children with multisystem inflammatory syndrome (MIS‐C), revealing rare structural and copy number variants in and near immune‐related genes, including ORAI1, STAT4, ITPR1, BATF, CFHR5, and DOCK2.
Catherine A. Brownstein   +57 more
wiley   +1 more source

The Density-Driven Winter Intensification of the Ross Sea Circulation

open access: yesJournal of Geophysical Research: Oceans, 2018
Stefan Jendersie   +3 more
semanticscholar   +1 more source

Unlocking the Future of Insurance: The Power of Open Data, Digital Transformation, and Human Talent

open access: yesHuman Resource Development Quarterly, EarlyView.
ABSTRACT Despite rapid technological advancement in insurance, there remains a critical gap in understanding how open data initiatives affect employee digital competencies and organizational transformation. This research investigates this relationship through a systematic review of 51 scholarly articles published between 2018 and 2024, using structured
Narongsak Sukma, Siriporn Yamnill
wiley   +1 more source

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