Results 241 to 250 of about 271,704 (308)

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Assessment of apical debris extrusion with three nickel-titanium rotary systems using conventional and lyophilization-based quantification methods. [PDF]

J Conserv Dent Endod
Hegde NN, Attavar S, Banerjee A, Harikrishna N, Lakshmi VC, Ravinanthanan M.   +5 more
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Evaluation of bending test, cyclic fatigue, and buckling resistance test using rotary Nickel-Titanium files of three types: An <i>in vitro</i> study. [PDF]

J Conserv Dent Endod
Jiffri S, Abumostafa A.
europepmc   +1 more source

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin, Sofia Waldorf, Janina von der Gablentz, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Julian Grosskreutz, Patrick Weydt, Sarah Bernsen   +8 more
wiley   +1 more source

Dissolution Rate and Stability Improvement of Hydrochlorothiazide and Valsartan by Co-Amorphous Formulation. [PDF]

Adv Pharmacol Pharm Sci
Abdulraheem AM, Alkhamis KA, Al-Nimry SS.   +2 more
europepmc   +1 more source

Comparison of post-operative pain between rotary and reciprocating file systems in root canal therapy: An <i>in vivo</i> study. [PDF]

Bioinformation
Ingale PC, Mehar S, Bora P, Ahmad MZ, Thakkar J, Gill S, Surana P.   +6 more
europepmc   +1 more source

A Three-Step Synthesis of Squalene from <i>trans, trans</i>-Farnesol. [PDF]

ACS Omega
Achtenhagen M, Silldorff T, Foster KHB, Barone T, Mal R, Bolessa E, Ellis A, Bahulekar R, Deorkar N, Sorensen EJ.   +9 more
europepmc   +1 more source

Real-world CAN bus dataset for agricultural tractor block load cycle characterization. [PDF]

Data Brief
Dana A, Özener O, Tellioğlu AC.
europepmc   +1 more source

A collaborative cervical precancer screening strategy with concurrent HPV genotyping and visual inspection using alumni of a training centre across Ghana: The Rotary 'Protect Your Pearl' initiative. [PDF]

PLoS One
Effah K, Ametefe DL, Amuah JE, Essel NOM, Afetor M, Dugbazah AE, Deho E, Kemawor S, Danyo S, Sesenu E, Tay G, Kitcher YT, Gedzah I, Williams I, Klutsey GB, Donkoh ET.   +15 more
europepmc   +1 more source