Results 131 to 140 of about 857,752 (305)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Miss Billie Burke, ca. 1905, 3 [picture] /

, 1900
Title from image.; Part of the collection: Postcard portraits of Miss Billie Burke, 1900-1910.; Inscriptions: "Miss Billie Burke"--Printed in centre below image; "Johnston & Hoffmann"--Printed lower left on image; "1935 K.

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Test and Analysis of Performance of Flat Single-axis Photovoltaic Tracking Bracket Multi-point Drive Rotary Reducers

Jixie chuandong
A new type of rotary reducer is urgently needed in engineering to improve the low efficiency of single point drive operation for flat single axis photovoltaic tracking brackets, in order to adapt to complex environments and reduce costs. For this purpose,
Ma Tao, Li Wei, Chen Xuehui, Gao Ting, Li Wei, Tang Xing   +5 more
doaj  

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

Rotary International Resolution

, 2012
A R}~SOLUTION TO DEFItlE TIlE POSITION OF ROTARY ITH HEGARD TO OBJECTIVE ACTIVITIES OFFERED J~Y THE ROTARY CLUE OF CHICAGO. WHEREAS, there appears to be a tendency to have Rotary Clubs asaume act i vities not within the soope of the ob­Jects of Rotar y ...
Rotary International
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The Four Way Test presented by the Rotary Club of Georgetown, Guyana

Presented to the Wilmington Rotary Club in recognition of their 100th anniversary in ...

core   +1 more source

Test and Analysis of Performance of Flat Single-axis Photovoltaic Tracking Bracket Multi-point Drive Rotary Reducer

Jixie chuandong
A new type of rotary reducer is urgently needed in engineering to improve the low efficiency of single point drive operation for flat single axis photovoltaic tracking brackets, in order to adapt to complex environments and reduce costs. For this purpose,
Ma Tao, Li Wei, Chen Xuehui, Gao Ting, Li Wei, Tang Xing   +5 more
doaj  

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Houston Rotary Bulletin

, 1918
Weekly bulletin of the Rotary Club of Houston providing updates about news, events, and other information of interest to Rotarians in the Houston area.
Rotary Club of Houston, Wilson, Fred T.
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CFD Analysis of Oil Discharge Rate in Rotary Compressor [PDF]

, 2012
Oil discharge rate in rotary compressor has a significant influence on heat transfer performance of condenser and evaporator in air conditioning system.
Wu, Jun, Liang, Shebing, Xu, Jia, Deng, Liying, Liu, Qiang   +4 more
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