Results 21 to 30 of about 36,363 (217)
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling +2 more
wiley +1 more source
Periodontal health in children with diabetes mellitus type 1 in Montenegro [PDF]
Introduction Separation of instruments in the root canal is one of the challenges in endodontic treatment. More specifically, nickel-titanium (NiTi) rotary instruments usually separate without previous deformation.
Đuričković Mirjana +4 more
doaj
Rotary instruments in the treatment of chronic periodontitis: A randomized clinical trial
Background: The study aimed at comparing the effectiveness of rotary instruments with hand instruments in non-surgical treatment of chronic periodontitis.
Parveen Dahiya, Reet Kamal
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Fracture of rotary nickel titanium instruments
With the advent of rotary nickel titanium (NiTi) instruments, preparation of curved canals have become easy but chances of instrument separation have increased.
Rajendra Kumar Tewari +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Deformation of nickel-titanium (NiTi) rotary instruments in cyclic loading: In vitro study [PDF]
Introduction Separation of instruments in the root canal is one of the challenges in endodontic treatment. More specifically, nickel-titanium (NiTi) rotary instruments usually separate without previous deformation.
Nešković Isidora +4 more
doaj
Objective: To compare the root canal preparation of primary teeth with reciprocating and rotary NiTi instruments. Material and Methods: Electronic databases (PubMed/MEDLINE, Web of Science, TRIP, Lilacs, Embase, and Scopus) were systematically searched ...
Laura Izabel Lampert Bonzanini +7 more
doaj
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

