Results 31 to 40 of about 944 (169)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Microcrack Formation after Root Canal Instrumentation: A Narrative Review [PDF]

Journal of Clinical and Diagnostic Research
The development of rotary files and other endodontic instrument techniques have revolutionised treatment by enhancing canal preparation and producing rounder, smoother canals that are constructed of Nickel-Titanium (NiTi) alloy.
Divya Naik, Amisha Saoji, Sumanthini Margasahayam, Anuradha Patil, Shouvik Ganguly   +4 more
doaj   +1 more source

Evaluation of stress distribution in nickel-titanium rotary instruments with different geometrical designs subjected to bending and torsional load: a finite element study

Bulletin of the National Research Centre, 2020
Introduction Geometrical designs of nickel-titanium (NiTi) rotary instruments have a considerable influence on their mechanical performance, and thereby have the tendency to fracture.
Manar Galal, Tamer M. Hamdy
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Influence of Axial Movement on Fatigue of Profile® Ni-Ti Rotary Instruments: an in vitro evaluation

Biomolecules & Biomedicine, 2010
The aim of this study was to evaluate the influence of the axial movement and the angle of curve (in degrees) on fatigue of nickel-titanium (Ni-Ti) ProFile’ rotary endodontic instruments.
Marie-Chantal Avoaka, Youssef Haïkel
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Fatigue behavior of lubricated Ni-Ti endodontic rotary instruments

Fracture and Structural Integrity, 2014
The use of Ni-Ti alloys in the practice of endodontic comes from their important properties such as shape memory and superelasticity phenomena, good corrosion resistance and high compatibility with biological tissues.
A. Brotzu, F. Felli, C. Lupi, C. Vendittozzi, E. Fantini   +4 more
doaj  

Corrosion of Ni-Ti Rotary Instruments: A Review [PDF]

Journal of Dental Materials and Techniques, 2019
The nickel-titanium (Ni-Ti) alloys used in endodontics contain 56% Ni and 44% Ti. The 2 unique features related to clinical dentistry (i.e., shape memory effect and superelasticity) are due to the transition from austenite to martensite in Ni-Ti alloy ...
Zahed Mohammadi, Jun-Ichiro Kinoshita, Atsufumi Manabe, Mikihiro Kobayashi, Sousan Shalavi, Hamid Jafarzadeh   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source