Results 61 to 70 of about 14,169,342 (275)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Inertial convection in rotating fluid spheres [PDF]

, 2004
The onset of convection in the form of inertial waves in a rotating fluid sphere is studied through a perturbation analysis in an extension of earlier work by Zhang (1994).
Simitev, R., Busse, F.H.
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Association of breakfast skipping with habitual dietary intake and BMI in female rotating shift workers

Public Health Nutrition, 2023
Objective: Higher BMI, lower quality of diet and a higher percentage of breakfast-skippers have been reported among rotating shift (RS) workers compared with day shift (DS) workers. As such, this study examined the association between breakfast skipping,
Takahiro Yoshizaki, Taiki Komatsu, Yuki Tada, Fumiharu Togo   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Night shift work and modifiable lifestyle factors [PDF]

, 2014
Objectives: Night shift work has been linked to some chronic diseases. Modification of lifestyle by night work may partially contribute to the development of these diseases, nevertheless, so far epidemiological evidence is limited.
Wojciech Sobala, Marcin Rybacki, Bukowska, Agnieszka, Marcinkiewicz, Andrzej, Jolanta Krysicka, Rybacki, Marcin, Klimecka-Muszyńska, Dorota, Beata Pepłońska, Burdelak, Weronika, Weronika Burdelak, Pepłońska, Beata, Agnieszka Bukowska, Krysicka, Jolanta, Sobala, Wojciech, Dorota Klimecka-Muszyńska, Andrzej Marcinkiewicz   +15 more
core   +2 more sources

Impact of Shift Work Patterns on Actigraphy-based Sleep Measures among Nurses: Results from the Hong Kong Night Shift Cohort

Asian Journal of Social Health and Behavior
Introduction: The relationship between sleep quality and shift work schedules among nurses remains unclear. To assess sleep parameters across different shifts, with particular focus on a rapid-rotating shift pattern (completing afternoon→morning→night ...
Beixi Li, Choi Miu Wan, Priscilla Ming Yi Lee, Shirong Qiu, Anke Huss, Yuen Ting Julie Ma, Joey Wing-Yan Chan, Amy Wing-Yin Ho, Chung Shun Ho, Jean H. Kim, Yun Kwok Wing, Lap Ah Tse   +11 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source