Results 241 to 250 of about 47,611 (304)
Free-running ultraviolet dual comb spectroscopy enabling absolute electronic fingerprinting. [PDF]
Fürst L +8 more
europepmc +1 more source
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang +16 more
wiley +1 more source
Polarized Phase-Sensitive Fluorescence-Image Correlation Spectroscopy. [PDF]
Clayton AHA.
europepmc +1 more source
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Assessing the Limits of the "Lego-Brick" Approach: Equilibrium Structures of Strained and Flexible Cyclic Molecules. [PDF]
Alessandrini S +4 more
europepmc +1 more source
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Methylsalicylate: A Rotational Spectroscopy Study
The Journal of Physical Chemistry A, 2007We report the free-jet rotational spectra of methylsalicylate, a molecule with a possible tautomeric and conformational equilibrium. In the ground electronic state, the molecule adopts a form stabilized by an intramolecular hydrogen bond between the phenolic hydrogen and the carbonylic oxygen, and this structure is characterized as the lowest-energy ...
MELANDRI, SONIA +6 more
openaire +3 more sources

