Results 241 to 250 of about 47,611 (304)

Free-running ultraviolet dual comb spectroscopy enabling absolute electronic fingerprinting. [PDF]

open access: yesPhotonix
Fürst L   +8 more
europepmc   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

Revisiting the <i>J</i> = 1 ← 0 fundamental rotational transition of HHe<sup>+</sup> with action spectroscopy.

open access: yesPhys Chem Chem Phys
Asvany O   +11 more
europepmc   +1 more source

High-resolution spectroscopy of [H,C,N]<sup>+</sup>: I. Rotationally resolved vibrational bands of HCN<sup>+</sup> and HNC.

open access: yesPhys Chem Chem Phys
Schmid PC   +7 more
europepmc   +1 more source

Methylsalicylate:  A Rotational Spectroscopy Study

The Journal of Physical Chemistry A, 2007
We report the free-jet rotational spectra of methylsalicylate, a molecule with a possible tautomeric and conformational equilibrium. In the ground electronic state, the molecule adopts a form stabilized by an intramolecular hydrogen bond between the phenolic hydrogen and the carbonylic oxygen, and this structure is characterized as the lowest-energy ...
MELANDRI, SONIA   +6 more
openaire   +3 more sources

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