Results 91 to 100 of about 64,554 (238)
Efficacy and Safety of Messenger RNA Vaccines
ABSTRACT Background and Aims The rapid development of mRNA vaccines has revolutionized infectious disease prevention and cancer immunotherapy. While their efficacy is well established, concerns about safety and immunopathological risks persist. This study aims to evaluate the immunogenicity, safety profiles, and design considerations of mRNA vaccines ...
Kesaobaka Batisani, David Chisompola
wiley +1 more source
HSV-replication defective based vector as vaccines against Rotavirus infections
Background: Rotaviruses (RVs) are the most important cause of acute gastroenteritis in humans and animals. These viruses cause diarrheal disease primarily in the young, but infection and disease in older children and adults can occur, resulting in more ...
Facciolo, Sabrina
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Pharmacy‐Based Immunization Delivery: A Comprehensive History and Current Challenges
ABSTRACT Pharmacists and their teams have a long history of involvement with vaccines. This paper describes the contributions of pharmacy‐based immunization delivery in the United States from the 1800's to date. Early activities centered around storage and distribution of antitoxins and vaccines. From the 1950s through the early 1990s, pharmacists were
Jean‐Venable R. Goode +4 more
wiley +1 more source
Rotavirus 993/83, isolated from calf faeces, closely resembles an avian rotavirus [PDF]
Polypeptides from purified virions of the calf rotavirus (RV) isolate 993/83 and those from the pigeon RV isolate PO-13 comigrated on SDS-polyacrylamide gels. Two polypeptides of 45K and 47K were detected at the position of VP6.
Eichhorn, Werner +7 more
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Porcine rotavirus mainly infects primary porcine enterocytes at the basolateral surface
Intestinal epithelium functions as a barrier to protect multicellular organisms from the outside world. It consists of epithelial cells closely connected by intercellular junctions, selective gates which control paracellular diffusion of solutes, ions ...
Tingting Cui +3 more
doaj +1 more source
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Introduction: Prior to 2006, nearly every U.S. child was infected with rotavirus by 5 years of age, and rotavirus was the leading cause of severe childhood gastroenteritis.
Talia Pindyck +2 more
doaj +1 more source
Rotavirus symptomatic infection among unvaccinated and vaccinated children in Valencia, Spain
Background Human group A rotavirus is the leading cause of severe acute gastroenteritis in young children worldwide. Immunization programs have reduced the disease burden in many countries. Vaccination coverage in the Autonomous Region of Valencia, Spain,
Raúl Pérez-Ortín +5 more
doaj +1 more source
Green Stool Predominance in Babies and Subsequent Bowel Function at 1–2 Years of Age
ABSTRACT Aim To study the relationship between bowel function after birth and at 1–2 years of age in the prospective HELMi cohort of term infants. Methods We focused on infants with predominantly green stools (n = 152) for three consecutive weeks in early life and their sex, age, and delivery mode‐matched controls (n = 300), and evaluated bowel ...
L. Typpö +5 more
wiley +1 more source
Characterization of a Second Bovine Rotavirus Serotype [PDF]
Bovine rotavirus (BRV) V 1005 was characterized by two-way cross-neutralization tests as a second serotype of BRV. Virions and inner shell particles of 65 nm and 55 nm diameter respectively, and empty capsids of 65 nm and 55 nm diameter were separated by
Fryder, V. +4 more
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