Results 71 to 80 of about 49,234 (199)

Actinomycin Derivatives: Structural Diversification and Biological Activities

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley   +1 more source

Rotavirus Pathogenicity

Virology, 1996
The pathogenicity of rotaviruses depends on multiple viral and host factors. In this review the evidence for the involvement of a number of viral genes in the ability to cause disease is presented. Different genes are of importance in different rotavirus-host systems: there is no single pathogenicity factor.
Burke, B, Desselberger, U
openaire   +3 more sources

Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong, Eunsoo Kim, Yong Sung Kim, Eunok Im   +3 more
wiley   +1 more source

Surveillance of Rotavirus Diarrhea in Hasan Sadikin Hospital Bandung

Majalah Kedokteran Bandung, 2010
The diarrhea morbidity in Indonesia has increased, however, all the reports had not been done carefully, so that accurate surveillance are essential for improving quality of morbidity data.
Dwi Prasetyo, Iesje Martiza, Yati Soenarto   +2 more
doaj   +1 more source

Seasonal Trends, Environmental Drivers, and Lessons Learned From the 2023 Cholera Outbreak in Chattogram, Bangladesh: A Descriptive Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Acute watery diarrhea (AWD) remains a major global public health problem, and cholera continues to cause substantial morbidity and mortality in settings with inadequate water, sanitation, and hygiene (WASH). Chattogram, a coastal district of Bangladesh, is particularly vulnerable due to seasonal hydroclimatic changes ...
Immamul Muntasir, Md. Jahidur Rahman, Sayik Bin Alam, Abir Shaqran Mahmood, Tanvir Ahmed, Mithun Bahadur, Farzana Islam Khan, Kyaw Thowai Prue Prince, Mohammad Rashedul Hassan, Zakir Hossain Habib, Tahmina Shirin   +10 more
wiley   +1 more source

Epidemiology of rotavirus in the Iranian children: A systematic review and meta-analysis

Journal of Global Infectious Diseases, 2017
Rotavirus is associated with increased risk for severe diarrhea in infants and young children worldwide. This systematic review and meta-analysis was performed to determine the prevalence rate of rotavirus from different parts of Iran and provide an ...
Seyed Hamid Reza Monavari, Shima Hadifar, Shayan Mostafaei, Ali Miri, Mohsen Keshavarz, Farhad Babaei, Mohsen Moghoofei   +6 more
doaj   +1 more source

Revealing Sex Disparities in the Burden of Diarrheal Diseases Among Children Under 5: Global and Asian Trends and Projections, 1990–2050 – A Population‐Based Observational Analysis Using GBD 2021 Data

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Although the global burden of diarrheal diseases (DDs) among children under 5 years of age has declined substantially over recent decades, sex‐specific disparities and regional heterogeneity across Asia—particularly regarding non‐fatal outcomes—remain insufficiently characterized.
Maedeh Amini, Paria Dehesh, Melina Farshbafnadi, Elaheh Dehghani   +3 more
wiley   +1 more source

SNHG15 Positively Regulates Influenza Virus Infection Through Its Association With miR‐153 and RABL2A

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Influenza viruses cause seasonal epidemics, and current vaccines do not fully protect against them. This study focuses on long non‐coding RNAs (lncRNAs), which are RNA molecules that do not code for proteins but play crucial roles in various biological processes. We identified 17 lncRNAs altered by the influenza virus.
Samuel Pushparaj, Kishore Vaddadi, Chaoqun Huang, Yurong Liang, Dao Xu, Gayan Bamunuarachchi, Prince Jhandai, Keerthana Santhosh, Elizabeth Varghese, Lin Liu   +9 more
wiley   +1 more source

Histo-Blood Group Antigens in Children with Symptomatic Rotavirus Infection

Viruses, 2019
Group A rotaviruses are a major cause of acute gastroenteritis in children. The diversity and unequal geographical prevalence of rotavirus genotypes have been linked to histo-blood group antigens (HBGAs) in different human populations.
Raúl Pérez-Ortín, Susana Vila-Vicent, Noelia Carmona-Vicente, Cristina Santiso-Bellón, Jesús Rodríguez-Díaz, Javier Buesa   +5 more
doaj   +1 more source

Two Lineages of DS‐1‐Like G3P[8] Human Rotaviruses in Sabah, Malaysia: Genetic Diversity and Evidence of Reassortment

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Group A rotavirus (RVA) genotype G3P[8] strains typically carry a Wa‐like genomic backbone, but DS‐1‐like G3P[8] reassortants have disseminated globally since 2013. In Sabah, Malaysia, surveillance in 2018–2019 identified frequent G3P[8] strains with a short RNA electropherotype, consistent with DS‐1‐like backbones.
Yuki Akari, Lia Natasha Amit, Jecelyn Leaslie John, Daisuke Mori, Abraham Zefong Chin, Andau Konodan Mosiun, Saori Fukuda, Maurine Mumo Mutua, Ibuki Sato, Yoshimasa Maeno, Kamruddin Ahmed, Satoshi Komoto   +11 more
wiley   +1 more source