Results 31 to 40 of about 132,407 (263)

Global, Regional, and National Estimates of Rotavirus Mortality in Children <5 Years of Age, 2000-2013.

Clinical Infectious Diseases, 2016
BACKGROUND Rotavirus vaccine is recommended for routine use in all countries globally. To facilitate decision making on rotavirus vaccine adoption by countries, help donors prioritize investments in health interventions, and monitor vaccine impact, we ...
J. Tate, A. Burton, C. Boschi-Pinto, U. Parashar   +3 more
semanticscholar   +1 more source

Effectiveness of rotavirus vaccination in prevention of hospital admissions for rotavirus gastroenteritis among young children in Belgium : case-control study [PDF]

, 2012
Objective : To evaluate the effectiveness of rotavirus vaccination among young children in Belgium. Design : Prospective case-control study. Setting : Random sample of 39 Belgian hospitals, February 2008 to June 2010.
A. Vergison, A.-S. Maernoudt, E. Heylen, H. Capiau, J. De Koster, J. Matthijnssens, J.-Y. Pircon, K. Van Herck, L. Verdonck, M. Azou, M. Raes, M. Soriano-Gabarro, M. Van Ranst, M. Verghote, M. Zeller, N. Meyer, null null, P. Van Damme, T. Braeckman   +18 more
core   +1 more source

Putative E3 Ubiquitin Ligase of Human Rotavirus Inhibits NF-κB Activation by Using Molecular Mimicry To Target β-TrCP

mBio, 2015
NF-κB plays a critical role in the induction and maintenance of innate and adaptive immune transcriptional programs. An associated inhibitor of κB protein (IκB) regulates NF-κB activation and contains a degron motif (DSGΦxS) that undergoes ...
Marco Morelli, Allison F. Dennis, John T. Patton   +2 more
doaj   +1 more source

Intracellular neutralisation of rotavirus by VP6-specific IgG

PLoS Pathogens, 2020
Rotavirus is a major cause of gastroenteritis in children, with infection typically inducing high levels of protective antibodies. Antibodies targeting the middle capsid protein VP6 are particularly abundant, and as VP6 is only exposed inside cells ...
S. Caddy, M. Vaysburd, M. Wing, Stian Foss, J. Andersen, K. O'connell, Keith Mayes, Katie Higginson, M. Iturriza-Gómara, U. Desselberger, L. James   +10 more
semanticscholar   +1 more source

Rotavirus genetic diversity, disease association, and temporal change in hospitalized rural Kenyan children [PDF]

, 2010
Background. The effectiveness of rotavirus vaccines will be dependent on the immunity conferred against prevalent and emergent variants causing severe diarrheal disease.
Abwao, John, De Beer, Mariet C., Netshifhefhe, Lufuno, Nokes, D. James, Page, Nicola, Peenze, Ina, Seheri, Mapaseka, Steele, Duncan, Williams, Thomas N.   +8 more
core   +4 more sources

Rotavirus infections and climate variability in Dhaka, Bangladesh: a time-series analysis. [PDF]

, 2007
Attempts to explain the clear seasonality of rotavirus infections have been made by relating disease incidence to climate factors; however, few studies have disentangled the effects of weather from other factors that might cause seasonality.
Armstrong, B, Faruque, ASG, Hashizume, M, Hayashi, T, Sack, DA, Wagatsuma, Y   +5 more
core   +3 more sources

Rotavirus specific maternal antibodies and immune response to RV3-BB neonatal rotavirus vaccine in New Zealand

Human Vaccines & Immunotherapeutics, 2017
Background: Maternal antibodies, acquired passively via placenta and/or breast milk, may contribute to the reduced efficacy of oral rotavirus vaccines observed in children in developing countries.
Mee-Yew Chen, Carl D. Kirkwood, Julie Bines, Daniel Cowley, Daniel Pavlic, Katherine J. Lee, Francesca Orsini, Emma Watts, Graeme Barnes, Margaret Danchin   +9 more
doaj   +1 more source

Genotypic characterization of rotavirus in children under 5 years circulating in Côte D’Ivoire from 2010 to 2013

Virology Journal, 2018
Background Rotavirus infection is the most common cause of severe gastroenteritis in children under five years of age in both developed and developing countries.
Catherine Boni-cisse, Sindou Meite, Alice Britoh Mlan, Flore Zaba, Rebecca N’Guessan, Nicaise Aka Lepri, Bélinda Lartey   +6 more
doaj   +1 more source

Global Illness and Deaths Caused by Rotavirus Disease in Children

Emerging Infectious Diseases, 2003
To estimate the global illness and deaths caused by rotavirus disease, we reviewed studies published from 1986 to 2000 on deaths caused by diarrhea and on rotavirus infections in children.
U. Parashar, Erik Hummelman, J. Bresee, Mark A. Miller, R. Glass   +4 more
semanticscholar   +1 more source

Burden of disease and circulating serotypes of rotavirus infection in sub-Saharan Africa: systematic review and meta-analysis. [PDF]

, 2009
Two new rotavirus vaccines have recently been licensed in many countries. However, their efficacy has only been shown against certain serotypes commonly circulating in Europe, North America, and Latin America, but thought to be globally important.
Elisabeth Sanchez-Padilla, Rebecca F Grais, Philippe J Guerin, Andrew D Steele, Marie-Eve Burny, Francisco J Luquero, Ruiz-Palacios, Vesikari, Parashar, Estes, Santos, Kosek, Parashar, Gentsch, DerSimonian, Freeman, Clopper, Parashar, Steele, Anagonou, Kasule, Kebaabetswe, Basu, Esona, Koulla-Shiro, Armah, Armah, Binka, Silva, Armah, Asmah, Armah, Nakano, Nielsen, Fischer, Fischer, Fischer, Molbak, Akoua-Koffi, Nakata, Saidi, Cunliffe, Nokes, Kiulia, Cunliffe, Cunliffe, Cunliffe, Mandomando, Steele, Audu, Adah, Gomwalk, Adah, Salu, Odimayo, Gomwalk, Aminu, Adah, Avery, Audu, Pennap, Steele, Sebata, Mphahlele, Haffejee, Mnisi, Bos, Griffiths, Moyo, Steele, Mpabalwani, Tswana, Ferreccio, Kapikian, Iturriza-Gomara, Glass, Parez, Su-Arehawaratana, Patriarca, de Oliveira   +79 more
core   +2 more sources