Results 111 to 120 of about 43,428 (222)

PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target

Virulence, 2018
Rotavirus infection is a major cause of severe dehydrating diarrhea in infants younger than 5 y old and in particular cases of immunocompromised patients irrespective to the age of the patients. Although vaccines have been developed, antiviral therapy is
Yuebang Yin, Wen Dang, Xinying Zhou, Lei Xu, Wenshi Wang, Wanlu Cao, Sunrui Chen, Junhong Su, Xuepeng Cai, Shaobo Xiao, Maikel P. Peppelenbosch, Qiuwei Pan   +11 more
doaj   +1 more source

Epidemiology of rotavirus infection in children in Blantyre, Malawi, 1997-2007.

, 2010
Acute gastroenteritis caused by rotavirus infection is an important cause of morbidity and mortality among infants and young children in Africa. From 1997 through 2007, we enrolled 3740 children .001).
Dove, Winifred, Molyneux, Malcolm E, Hart, C Anthony, Winifred Dove, Nigel A. Cunliffe, Bagrey M. Ngwira, Thindwa, Benson DM, Broadhead, Robin L, Benson D. M. Thindwa, Cunliffe, Nigel A, C. Anthony Hart, Ngwira, Bagrey M, Robin L. Broadhead, Malcolm E. Molyneux, Turner, Ann M, Ann M. Turner   +15 more
core   +1 more source

НАРУШЕНИЯ МЕТАБОЛИЧЕСКОЙ АКТИВНОСТИ КИШЕЧНОЙ МИКРОФЛОРЫ И МЕСТНОГО ИММУНИТЕТА ПРИ РОТАВИРУСНОЙ ИНФЕКЦИИ

, 2020
The paper describes the research on metabolic activity of intestinal microflora and secretory immunoglobulin A (sIgA) content in coprofiltrate of rotavirus infection patients depending on disease course.
Г. П. Мартынова, И. А. Соловьева, I. A. Solovyeva, Н. В. Коган, G. P. Martynova, N. V. Kogan   +5 more
core   +1 more source

The epidemiology and disease burden of rotavirus infection in the Salento peninsula, Italy

, 2008
Background. - To delineate the epidemiology of acute illnesses of the gastro-enteric tract in the Salento, with particular reference to infections sustained by rotaviruses. Methods.
GABUTTI, Giovanni, GRASSI T, GUIDO M, DE DONNO A, the Collaborative Group for the surveillance of Rotavirus infection   +4 more
core  

The aetiology of infectious intestinal disease in the community in Malta [PDF]

, 2010
Routine sources of data provide limited information on aetiological agents causing infectious intestinal disease (IID) in the community. A retrospective, age-stratified, cross-sectional, telephone study at community level was performed whereby identified
Gauci, Charmaine, Ruggieri, Franco-Maria, Mamo, Julian, Cuschieri, Liliana, Barbara, Christopher, Gilles, Herbert, Bartolo, Ilaria di   +6 more
core  

Pseudo-outbreak of rotavirus infection in a neonatal intensive care unit

, 2017
Background: A rotavirus outbreak in a neonatal intensive care unit (NICU) may have catastrophic consequences for young infants receiving critical care.
Tan, Boon Fatt;Chen, Yee-Chun;Lee, Chun-Nan;Chang, Luan-Yin;Hsieh, Wu-Shiun;Tsao, Po-Nien;Liu, Ying-Chieh;Chen, Mei-Ling;Ho, Shu-Yuan;Lu, Chun-Yi;Huang, Li-Min, 呂俊毅;李君男;曹伯年;謝武勳;黃立民;陳宜君;張鑾英;何淑媛   +1 more
core   +1 more source

Role of nitric oxide during rotavirus infection

, 2006
The pathophysiological mechanisms behind rotavirus-induced diarrhoea still remain incomplete. Current views suggest that the non-structural protein 4 (NSP4) of rotavirus and the enteric nervous system (ENS) participate in water secretion and diarrhoea ...
Svensson, Lennart, Sundqvist, Tommy,, Rodriguez-Diaz, J, Svensson, Lennart,, Buesa, Javier, Espinoza, F, Espinoza, Felix, Istrate, Claudia, Istrate, C, Sundqvist, T, Banasaz, Mahanez, Rottenberg, Martin, Sundqvist, Tommy, Svenssons, L, Lundgren, Ove, Buesa, J, Lundgren, O, Rodriguez-Diaz, Jesús, Banasaz, M, Lundgren, Ove,, Rottenberg, M,   +20 more
core   +2 more sources

Wastewater concentrations of rotavirus RNA are associated with infection and vaccination metrics in the USA

npj Viruses
Surveillance of rotavirus infections remains critical because vaccines are underutilized in the USA. Using wastewater solids measurements of rotavirus RNA collected over one year from 185 wastewater treatment plants (WWTPs) in the USA, we inferred ...
Elana M. G. Chan, Alessandro Zulli, Alexandria B. Boehm   +2 more
doaj   +1 more source

Functional studies of the group A rotavirus non-structural protein NSP4 [PDF]

NSP4, encoded by rotavirus genome segment 10 has been shown to be a transmembrane, endoplasmic reticulum (ER) specific N-linked glycoprotein. Consistent with its localization to the ER membrane, NSP4 was first shown to have a role in the morphogenesis
Yang, Weiming
core  

The importance of recent infection with Mycobacterium tuberculosis in an area with high HIV prevalence: a long-term molecular epidemiological study in Northern Malawi.

, 2005
BACKGROUND: The proportion of cases of tuberculosis due to recent infection can be estimated in long-term population-based studies using molecular techniques.
Yates, Malcolm D, Fine, Paul EM, Ngwira, Bagrey M., Traore, Hamidou, Crampin, Amelia C., Yates, Malcolm D., Fine, Paul E.M., Glynn, Judith R., Mwaungulu, Frank D., Glynn, Judith R, Mwaungulu, Frank D, Crampin, Amelia C, Drobniewski, Francis, Ndlovu, Richard, Ngwira, Bagrey M   +14 more
core   +1 more source