Results 41 to 50 of about 65,386 (216)

Clinical profile of children under 5 years of age with rotavirus diarrhoea in a hospital setting in Kisangani, DRC, after the introduction of the rotavirus vaccine, a cross-sectional study

BMC Pediatrics, 2023
Background The Democratic Republic of the Congo (DRC) is one of the countries with the highest rotavirus mortality rate in the world. The aim of this study was to describe the clinical features of rotavirus infection after the introduction of rotavirus ...
Didier Gbebangi-Manzemu, Véronique Muyobela Kampunzu, Hortense Malikidogo Vanzwa, Mupenzi Mumbere, Gaspard Mande Bukaka, Bibi Batoko Likele, Emmanuel Tebandite Kasai, Benoit Mbiya Mukinayi, Serge Tonen-Wolyec, Nestor Ngbonda Dauly, Jean Pierre Alworong’a Opara   +10 more
doaj   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Molecular Detection of Rotavirus Infection Associated with Diarrhoea among Children Aged 0 – 5 Years Attending Jahun General Hospital, Jigawa State

Sokoto Journal of Medical Laboratory Science, 2020
Group A Rotavirus causes infectious, severe and dehydrating diarrhoea which has great impact on childhood morbidity and mortality worldwide. However, there are limited data on this subject matter in the study area.
Kaila, M. , Sarkinfada, F. , Yusuf, M.M.* , Musa, Y.I.
doaj  

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

A Numerical Guide to Volume 2 of the Guidelines and Practical Advice on how to Transpose them into National Standards [PDF]

, 2008
[INTRODUCTION] In 2006, the World Health Organization published the third edition of the Guidelines, in collaboration with FAO and UNEP. The third edition consist of four volumes; volume 2, explained in this guidance note, addresses methods, procedures ...
Mara, D.D.
core  

Scope for rotavirus vaccination in India: revisiting the scientific evidence.

, 2011
Rotavirus vaccines have been developed to prevent deaths resulting from severe diarrhea of rotavirus origin. The use of vaccines as an intervention at scale to prevent and control the burden of rotavirus diarrhea is supported by the argument that ...
Hasan, Habib, Neogi, Sutapa Bandyopadhyay, Sheikh, Kabir, Zodpey, Sanjay   +3 more
core   +1 more source

Rotavirus and adenovirus infections in children with acute gastroenteritis after introducing the Rotasiil® vaccine in Kisangani, Democratic Republic of the Congo.

PLoS ONE
BackgroundAlthough rotavirus vaccination has reduced the global burden of the virus, morbidity and mortality from rotavirus infection remain high in Sub-Saharan Africa.
Didier Gbebangi Manzemu, Jean Pierre Alworong'a Opara, Emmanuel Tebandite Kasai, Mupenzi Mumbere, Véronique Muyobela Kampunzu, Bibi Batoko Likele, Naura Apio Uvoya, Hortense Malikidogo Vanzwa, Gaspard Mande Bukaka, Falay Sadiki Dady, Nestor Ngbonda Dauly, Laurent Belec, Serge Tonen-Wolyec   +12 more
doaj   +1 more source

The economic burden of rotavirus infection in South Korea from 2009 to 2012.

PLoS ONE, 2018
Rotavirus is a common cause of diarrhea worldwide, and vaccination prevents rotaviral gastroenteritis. Since the rotavirus vaccine was introduced in Korea in 2007, the prevalence of rotaviral gastroenteritis has decreased. However, little is known on the
Kyung Suk Lee, Ye-Rin Lee, So-Youn Park, In-Hwan Oh   +3 more
doaj   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

Quantifying health risks in wastewater irrigation [PDF]

, 2008
The guidelines developed by the World Health Organization for the safe use of wastewater in agriculture are based on a tolerable additional disease burden of 10-6 disability-adjusted life year loss per person per year, equivalent to rotavirus disease and
Mara, D.D.
core