Results 101 to 110 of about 696,195 (244)

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

open access: yesJournal of the American Geriatrics Society, Volume 74, Issue 3, Page 636-647, March 2026.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui   +11 more
wiley   +1 more source

Why does the world need another rotavirus vaccine?

open access: yesTherapeutics and Clinical Risk Management, 2008
Richard L Ward1, Monica M McNeal1, A Duncan Steele21Division of Infectious Diseases, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA; 2Initiative for Vaccine Research, World Health Organization, Geneva, SwitzerlandAbstract: A
Richard L Ward   +2 more
doaj  

Lower Coverage Rates of Full Rotavirus Vaccine Series in Libyan Children: A Prospective Cross-Sectional Study, 2016

open access: yesIranian Journal of Public Health, 2020
Background: There are little data on the current condition of national immunization programme (NIP) in Libya. In 2013, pentavalent rotavirus vaccines were added to the NIP.
Salem ALKOSHI, Eyal LESHEM
doaj   +1 more source

Effectiveness of pneumococcal conjugate vaccine and rotavirus vaccine introduction into the South African public immunisation programme [PDF]

open access: yes, 2014
KMImmunisation has contributed greatly to the control of vaccine-preventable diseases and therefore to improvements in health and survival, especially among young children, and remains one of the most successful and cost-effective public health ...
Bamford, L, Madhi, S.A, Ngcobo, N
core   +1 more source

Vaccine Candidates Designed to Prevent Enterotoxigenic Escherichia coli Diarrhoea: A Scoping Review of Clinical Trials Evaluating Vaccine Candidates in Development

open access: yesTropical Medicine &International Health, Volume 31, Issue 3, Page 295-306, March 2026.
ABSTRACT Objectives The primary objectives of this study are to (1) summarise the current landscape of ETEC vaccine development by describing, characterising and comparing ETEC vaccine candidates in clinical development, (2) assess key characteristics of the phases 1, 2 and 3 clinical trials that have been designed to evaluate ETEC vaccines in ...
Vaidehi Nafade   +4 more
wiley   +1 more source

Prevention of rotavirus gastroenteritis in infants and children: rotavirus vaccine safety, efficacy, and potential impact of vaccines

open access: yesBiologics: Targets & Therapy, 2010
Aruna Chandran1, Sean Fitzwater1, Anjie Zhen2, Mathuram Santosham11Department of International Health, Division of Health Systems, 2Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD ...
Aruna Chandran   +3 more
doaj  

A Review of Current Computational Tools for Peptide–Protein Docking

open access: yesJournal of Computational Chemistry, Volume 47, Issue 5, 15 February 2026.
In this review, we compare 14 specialized peptide‐protein docking programs, adaptable small‐molecule docking tools, and emerging AI‐driven approaches. By clarifying how each method works, we offer researchers an accessible guide to selecting the most suitable tools for biochemical studies and peptide‐focused drug discovery.
Fábio G. Martins   +2 more
wiley   +1 more source

Available evidence on the co-administration of the four-component meningococcal B vaccine (4CMenB) with three vaccines at the same visit among pediatric individuals

open access: yesHuman Vaccines & Immunotherapeutics
Vaccine co-administration is a useful strategy for improving vaccine coverage and adherence. In Italy, an update to the national immunization program (NIP) in 2023 included recommendations for co-administration of pediatric vaccines, including the four ...
Paolo Bonanni   +7 more
doaj   +1 more source

Macaque models of human infectious disease. [PDF]

open access: yes, 2008
Macaques have served as models for more than 70 human infectious diseases of diverse etiologies, including a multitude of agents-bacteria, viruses, fungi, parasites, prions.
Abe   +330 more
core   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

open access: yesAdvanced Science, Volume 13, Issue 10, 18 February 2026.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang   +7 more
wiley   +1 more source

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