Results 121 to 130 of about 813,317 (386)

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska   +18 more
wiley   +1 more source

Intelligent Design Method for Thermal Conductivity Topology Based on a Deep Generative Network

open access: yesChinese Journal of Mechanical Engineering
Heat dissipation performance is critical to the design of high-end equipment, such as integrated chips and high-precision machine tools. Owing to the advantages of artificial intelligence in solving complex tasks involving a large number of variables ...
Qiyin Lin   +7 more
doaj   +1 more source

Mechanotransduction Activates Microglia and Impairs Phagocytosis in Stiff Amyloid‐β Plaques

open access: yesAdvanced Science, EarlyView.
The study constructs an in vitro Aβ plaque‐associated microglia model and uses SECM and SICM to in situ monitor changes in ROS levels, membrane permeability, and phagocytosis of microglia during Aβ clearance. It is found out that Aβ stiffness triggers microglial activation via the PIEZO1 mechanotransduction pathway, causing neuroinflammation and ...
Yulin Liu   +8 more
wiley   +1 more source

Friction power loss in ball bearings: Correlation with bearing skidding and cage motion stability

open access: yesFriction
This study introduces a prediction method for bearing friction power loss, focusing on the interplay of bearing skidding and cage motion stability on the tribological properties of ball bearings.
Mingkai Wang   +5 more
doaj   +1 more source

Biomimetic Microfluidic Pumps for Selective Oil–Water Separation

open access: yesAdvanced Science, EarlyView.
A biomimetic spring microchannel system, utilizing advanced 3D printing technique, achieves swift and efficient oil‐water separation with over 99% efficiency. This innovative design leverages surface wettability and handles various oils, ensuring sustained performance and clog‐free operation for environmental remediation.
Zhaolong Wang   +8 more
wiley   +1 more source

Impact of Heat Treatment on the Rubbing Behavior of Bump-Type Foil Journal Bearing

open access: yesTribology Online
Under low-speed or start/stop conditions, the rubbing of top foil in foil journal bearing (FJB) prompting the application of heat treatment to improve the rubbing behavior of the foil bearing.
Vishal Mourya, Skylab P. Bhore
doaj   +1 more source

Characteristic Analysis and Simulated Test of Hybrid Bearing with the Introduction of Piezoelectric Controller

open access: yesShock and Vibration, 2016
A novel hybrid bearing with the introduction of piezoelectric controller and tilting pads to control vibration actively is proposed in this paper, and the feasibility of this scheme is verified by theoretical calculation and experimental data.
Runlin Chen   +4 more
doaj   +1 more source

Sustained‐Release Photothermal Microneedles for Postoperative Incisional Analgesia and Wound Healing via Hydrogen Therapy

open access: yesAdvanced Science, EarlyView.
This study introduces a novel transdermal delivery system of molecular hydrogen for postoperative pain relief and wound healing. This system utilizes sustained‐release photothermal microneedles to integrate hydrogen‐releasing nanoparticles and temperature‐responsive microspheres, achieving acid‐responsive hydrogen release and controlled drug release ...
Aining Zhang   +8 more
wiley   +1 more source

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