Results 131 to 140 of about 605,830 (356)

A New Actuator Surface Model with Improved Wake Model for CFD Simulations of Rotorcraft [PDF]

open access: yes, 2017
Simulations of rotorcraft operating in unsteady flow-fields, manoeuvring flight, or with complex rotor configurations pose a significant challenge to current simulation methods.
Barakos, Geogre   +3 more
core  

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

open access: yesAdvanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong   +12 more
wiley   +1 more source

Numerical hydrodynamic model of Awasan Bay, Surigao Del Norte, Philippines for tidal energy resource characterization

open access: yesDiscover Oceans
The Philippines is committed to reducing carbon emissions by shifting to renewable (e.g., tidal) energy. However, despite its abundant tidal energy resources, the localized characterization of its behavior in the country (e.g. Awasan Bay) remains limited.
Louis Irwin Questo, Mark Anthony Rotor
doaj   +1 more source

Numerical analysis of a variable camber rotor blade as a lift control device [PDF]

open access: yes
A new rotor configuration called the variable camber rotor was numerically investigated as a lift control device. This rotor differs from a conventional (baseline) rotor only in the blade aft section.
Awani, A. O., Stroub, R. H.
core   +1 more source

Surface‐Associated Proteins on Extracellular Vesicles Remodel the Tumor Microenvironment by Potentiating TGF‐β Signaling in a Contact‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li   +7 more
wiley   +1 more source

Test results from a dynamic model dynaflex rotor [PDF]

open access: yes, 1985
A one-fifth scale dynamic model of the Sikorsky Dynaflex rotor was tested in hover and in forward flight conditions in a wind tunnel. The Dynaflex rotor features an advanced composite structure which flexes to provide a constant speed universal joint ...
Goodman, R. K., Niebanck, C. F.
core   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

open access: yesAdvanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore   +20 more
wiley   +1 more source

Effect of rotor stiffness and lift offset on the aeroacoustics of a coaxial rotor in level flight [PDF]

open access: yes, 2009
The acoustic characteristics of a twin contra-rotating coaxial rotor configuration with significant flapwise stiffness are investigated in steady forward flight.
Brown, Richard   +2 more
core  

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

open access: yesAdvanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz   +10 more
wiley   +1 more source

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