Results 241 to 250 of about 56,466 (281)

Cardenolide‐Engineered Extracellular Vesicles Augment Drug Uptake and Cytotoxicity in Non‐small Cell Lung Cancer Cells

open access: yesSmall Methods, Volume 10, Issue 3, 9 February 2026.
Cardenolide‐functionalized extracellular vesicles enable targeted delivery of the chemotherapeutic doxorubicin to A549 lung cancer cells by binding Na+/K+‐ATPase, which is overexpressed in these cells. Surface‐modified, drug‐loaded EVs exhibit enhanced cytotoxicity compared to unmodified EVs and free drug, suggesting this system may lower the effective
Maja Dorfner   +7 more
wiley   +1 more source

Organelle Sorting and Proteomic Analysis to Identify Proteins Involved in the Uptake and Intracellular Trafficking of Nanoparticles

open access: yesSmall Methods, Volume 10, Issue 3, 9 February 2026.
A new method to identify proteins involved in the uptake and intracellular trafficking of nanoparticles is presented. After nanoparticle uptake, cells are lysed and the organelles with nanoparticles are purified using fluorescence assisted cell sorting. Next, their composition is determined by proteomic analysis.
Hector Garcia Romeu, Anna Salvati
wiley   +1 more source

Use of cesium chloride density gradient ultracentrifugation for the purification and characterization of recombinant adeno-associated virus. [PDF]

open access: yesEur Biophys J
Hirohata K   +9 more
europepmc   +1 more source

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