Results 111 to 120 of about 172,448 (289)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Electro-mechanical vibratory system [PDF]

open access: yes
The problem of predicting the phase angle of two self-synchronized rotors starting from rest is presented. It is shown that with insufficient power the rotors may not reach the final operating speed of the motors and stay locked at one of the lower ...
Paz, Mario
core   +1 more source

Computational spectroscopy of helium-solvated molecules: effective inertia, from small He clusters toward the nano-droplet regime

open access: yes, 2005
Accurate computer simulations of the rotational dynamics of linear molecules solvated in He clusters indicate that the large-size (nano-droplet) regime is attained quickly for light rotors (HCN, CO) and slowly for heavy ones (OCS, N$_2$O, CO$_2$), thus ...
Baroni, S.   +3 more
core   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

open access: yesAdvanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Effect of blade planform variation on the forward-flight performance of small-scale rotors [PDF]

open access: yes
An investigation was conducted in the Glenn L. Martin Wind Tunnel to determine the effect of blade planform variation on the forward-flight performance of four small-scale rotors.
Althoff, Susan L.   +3 more
core   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

open access: yesAdvanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha   +12 more
wiley   +1 more source

Generalized vortex-model for the inverse cascade of two-dimensional turbulence

open access: yes, 2013
We generalize Kirchhoff's point vortex model of two-dimensional fluid motion to a rotor model which exhibits an inverse cascade by the formation of rotor clusters.
A. S. Monin   +10 more
core   +1 more source

Reassigned Short Time Fourier Transform and K-means Method for Diagnosis of Broken Rotor Bar Detection in VSD-fed Induction Motors

open access: yesAdvances in Electrical and Computer Engineering, 2019
Over the years induction motors have established an uncanny knack for providing a plethora of utilities in the industry, where the fault monitoring and detection has become necessary.
OJEDA-AGUIRRE, N. A.   +5 more
doaj   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

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