Results 51 to 60 of about 1,619,251 (342)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Bending moment curvature relationship as an indicator of seismic resistance of older bridge piers
In seismic areas, it is recommended to design bridges characterized by ductile behaviour. A large number of existing bridges designed according to outdated standards, without guidelines for ductile behaviour detailing, can be found in seismically active ...
Mladen Srbić +2 more
doaj +1 more source
Tapol bulletin no, 144, December 1997 [PDF]
Contents:Troops open fire on students -- Timorese charged with explosive offences -- Suharto tells Mandela to mind his own business -- Spreading the word in Indonesia -- Abducted East Timorese speaks (II) -- Protests reverberate round the world ...
core
Multiagent model and mean field theory of complex auction dynamics [PDF]
Acknowledgements We are grateful to Ms Yinan Zhao for providing the data and to Yuzhong Chen and Cancan Zhou for discussions and suggestions. This work was supported by ARO under Grant No. W911NF-14-1-0504 and by NSFC under Grants Nos.
Chen, Qinghua +3 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Comparative Analysis of Steel Reinforced and Bamboo Reinforced Beams
This research will seek to compare bamboo reinforced concrete beams and steel reinforced concrete beams experimentally. Special emphasis will be laid on how both sets of beams respond to nominal moments.
Abdourahim Jallow +2 more
doaj +1 more source
Uncoupled material model of ductile fracture with directional plasticity [PDF]
Proposed paper deals with the application of plastic response with directional distortional hardening (DDH) in uncoupled ductile fracture model and comparison of the results with the same ductile fracture model based on isotropic J2 plasticity.
Dzugan, Jan +4 more
core
Does human imitate successful behaviors immediately? [PDF]
The emergence and abundance of cooperation in animal and human societies is a challenging puzzle to evolutionary biology. Over the past decades, various mechanisms have been suggested which are capable of supporting cooperation.
Lian-Zhong Zhang, Zhao-Jin Xu
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source

