Results 81 to 90 of about 1,619,251 (342)

Feature- and Face-Exchange illusions: New insights and applications for the study of the binding problem

open access: yesFrontiers in Human Neuroscience, 2014
The binding problem is a longstanding issue in vision science: i.e., how are humans able to maintain a relatively stable representation of objects and features even though the visual system processes many aspects of the world separately and in parallel ...
Arthur Gilman Shapiro   +2 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The influence of the hardening coolant agent on the properties of hot rolled bars of the steel 42CrMo4

open access: yesMetalurgija, 2014
In the work the influence results of two different hardening coolant agents on the basic mechanical proprieties and microstructure of the round hot rolled bars were presented.
M. Stańczyk, T. Figlus
doaj  

The ATLAS3D project - XXIV. The intrinsic shape distribution of early-type galaxies [PDF]

open access: yes, 2014
We use the ATLAS3D sample to perform a study of the intrinsic shapes of early-type galaxies, taking advantage of the available combined photometric and kinematic data. Based on our ellipticity measurements from the Sloan Digital Sky Survey Data Release 7,
Alatalo, Katherine   +25 more
core   +6 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

FE Simulation of the Stress-Strain State during Shear-Compression Testing and Asymmetric Three-Roll Rolling Process

open access: yesMATEC Web of Conferences, 2017
A three-roll rolling process is a significant technique in the production of wire rod, round bars and hexagonal profiles for structural applications. Better mechanical properties of wire rod, round bars and hexagonal profiles can be achieved due to large
Pesin Alexander   +3 more
doaj   +1 more source

Modeling and computation of necking instability in round bars using a total lagrangian elastoplastic formulation [PDF]

open access: yes, 2000
International audienceNecking is an instability phenomenon observed in round bars under tensile loading and has been investigated in numbers of works. In the present work, it is modeled within the framework of finite rate-independent plasticity.
Le Grognec, Philippe, Le Van, Anh
core   +1 more source

Central Mass Concentration and Bar Dissolution in Nearby Spiral Galaxies [PDF]

open access: yes, 2002
We use data from the BIMA Survey of Nearby Galaxies (SONG) to investigate the relationship between ellipticity and central mass concentration in barred spirals.
Aguerri J. A. L.   +10 more
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy