Results 191 to 200 of about 5,733 (291)

High‐Performance Bio‐Based Epoxy Vitrimers and Composites: Synergizing Robustness and Reprocessability via Fractional Free Volume Regulation

open access: yesAdvanced Science, EarlyView.
In this work, two bio‐based epoxy monomers were designed to tune the dynamic network of a rigid–flexible hybrid epoxy through free‐volume control, achieving a synergy among high free volume, high cross‐linking density, and segmental mobility while balancing strength and toughness.
Kai Dong, Di Zhao, Chengji Zhao
wiley   +1 more source

Targeted‐Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy

open access: yesAdvanced Science, EarlyView.
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing   +9 more
wiley   +1 more source

Acoustically Activatable Drug‐Loaded Nanodroplets for Mechanochemical Therapy in Solid Tumors

open access: yesAdvanced Science, EarlyView.
Microfluidically fabricated drug‐loaded nanodroplets are sequentially activated by dual‐frequency ultrasound through acoustic droplet vaporization followed by bubble collapse, enabling spatially controlled drug release and mechanical tumor fractionation, resulting in synergistic mechanochemotherapy and prolonged survival.
Tiran Bercovici   +4 more
wiley   +1 more source

Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications

open access: yesAdvanced Science, EarlyView.
Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu   +7 more
wiley   +1 more source

Sea Cucumber‐Inspired Double‐Network Biopolymer Hydrogels for Programmable Soft Machines

open access: yesAdvanced Science, EarlyView.
Inspired by the mutable dermis of sea cucumbers, the collagen‐alginate double‐network elastomeric (CoDE) hydrogel achieves programmable, recoverable, and functional mechanical behavior. The CoDE hydrogel mimics the mutable stiffness of the sea cucumber dermis through a densified collagen cryogel scaffold that is secondarily reinforced by a dissipative,
Luo Yan   +3 more
wiley   +1 more source

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